The epidemiology of NAFLD in Mainland China with analysis by adjusted gross regional domestic product: a meta-analysis.

Hepatology International
Yuankai WuMindie H Nguyen

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease worldwide. This study aimed to estimate the prevalence, incidence, and outcome of NAFLD in the large and diverse population of Mainland China. PubMed, Embase, and the Cochrane Library databases were searched to identify published studies with NAFLD epidemiology data in adult participants (≥ 18 years old) from Mainland China. Random effects models were used to determine pooled estimates. We screened 1,328 studies and included 167 eligible studies (participant n = 1,486,635): 149 studies (n = 1,350,819) for prevalence, 18 studies (n = 147,316) for incidence, 7 studies (n = 5446) for evolution of hepatic steatosis, and 2 studies (n = 647) for mortality analysis. The NAFLD prevalence of the overall populations was 29.88%, with higher rates in males, increasing age and increasing gross regional domestic product (GRDP) per capita (all p ≤ 0.010). The prevalence was the highest in North China (36.41%; higher in Uyghur and Hui Chinese 40.86% and 34.36% vs 28.11% in Han Chinese), higher in diabetics (51.83% vs. 30.76% in non-diabetics) and in obese participants (66.21% vs. 11.72% in lean). The NAFLD incidence was 56.7 (95% CI 47.4-66.8) per 1000 person...Continue Reading

References

Apr 3, 2013·The American Journal of Gastroenterology·Wendy H OddyLeon A Adams
May 15, 2013·Journal of Hepatology·Hui-Jie ZhangXiao-Ying Li
Dec 18, 2013·Arquivos brasileiros de endocrinologia e metabologia·Wen CaiHua Yao
Dec 15, 2015·The International Journal of Behavioral Nutrition and Physical Activity·Samantha M AttardPenny Gordon-Larsen
Dec 29, 2015·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Zobair M YounossiMark Wymer
Oct 21, 2016·European Journal of Gastroenterology & Hepatology·Takuya FukudaMichiaki Fukui
Sep 22, 2017·Therapeutic Advances in Gastroenterology·Shanhu QiuUwe Schumann
Jun 17, 2018·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Zobair YounossiUNKNOWN Global Nonalcoholic Steatohepatitis Council
Jan 5, 2019·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Luis Calzadilla-BertotLeon A Adams
May 10, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Feng ZhouHongliang Li
Aug 8, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Yuankai WuRamsey C Cheung

❮ Previous
Next ❯

Citations

Aug 25, 2020·Hepatology Communications·Rui HuangChao Wu
Jan 30, 2021·World Journal of Clinical Cases·Liang DaiGuang Ji
Apr 10, 2021·Transplant International : Official Journal of the European Society for Organ Transplantation·Wen Hui LimMark D Muthiah
Jul 3, 2021·Journal of Clinical Laboratory Analysis·Renling YaoChao Wu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Feng ZhouHongliang Li
Digestive Diseases
Stefano BellentaniGiorgio Bedogni
Nature Reviews. Gastroenterology & Hepatology
Isobel Leake
Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology
Sui-Weng Wong, Wah-Kheong Chan
© 2021 Meta ULC. All rights reserved