The epidemiology of nevi and signs of skin aging in the adult general population: Results of the KORA-survey 2000

The Journal of Investigative Dermatology
Torsten SchäferKORA Study Group

Abstract

Nevi can approximate the melanoma risk and demographic changes will increase the meaning of signs of skin aging (SSA). However, little is known about the epidemiology of nevi and SSA in the general adult population. We aimed to estimate the prevalence and age distribution of common and atypical nevi and SSA as well as gender differences in a large population-based sample. Within the Cooperative Health Research in the Augsburg Region (KORA) in Germany, a population-based survey was performed. Data were gathered by interview and the number of pigmented lesions and presence of SSA were obtained by dermatological examination. A total of 2,823 adults (mean age 49 years, 50% women) participated (response 67%). Most subjects (60.3%) exhibited 11 to 50 common nevi and 5.2% had at least one atypical nevus. 51.9% were diagnosed with elastosis (Cutis rhomboidalis nuchae, 18.3%; Morbus Favre Racouchot 1.4%). Ephelides were seen in 16%, lentigines solaris in 62.4%, and lentigines seniles in 33.2%. All signs of skin aging increased significantly with age and so did lentigines solaris, seniles, and actinic keratoses. In contrast, common and atypical nevi and ephelides decreased significantly with age. Signs of skin aging are frequent and incr...Continue Reading

References

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Citations

May 27, 2009·The British Journal of Dermatology·A NiederkornR Hofmann-Wellenhof
Dec 8, 2011·Pigment Cell & Melanoma Research·Judith WendtIchiro Okamoto
Apr 23, 2015·International Journal of Cosmetic Science·G DobosJ Kottner
Apr 22, 2014·Journal of Acupuncture and Meridian Studies·Forrest Cooper
Jul 20, 2014·Aging Clinical and Experimental Research·Hui-Wen TsengChieh-Shan Wu
May 11, 2016·Journal of Tissue Viability·Elisabeth HahnelJan Kottner
Mar 30, 2013·Anais Brasileiros De Dermatologia·Eudes Euler de Souza LucenaKenio Costa de Lima
Oct 31, 2007·Archives of Dermatological Research·Sen YangXue-Jun Zhang
Feb 29, 2008·Archives of Dermatological Research·Andrew M AltmanEckhard U Alt
May 28, 2019·Journal of Biosocial Science·Chantel F PheifferMichael J White
Apr 11, 2019·Melanoma Research·Philippe Autier, Jean-François Doré
Aug 17, 2019·Frontiers in Cell and Developmental Biology·Leopold EckhartFlorian Gruber
May 26, 2018·The Australasian Journal of Dermatology·Seohee Deanne ChoiWolfgang Weninger
Jul 13, 2018·JAMA Dermatology·John Hornberger, Daniel M Siegel
Feb 21, 2019·Archives of Dermatological Research·R L RaynerS S Dhaliwal
May 29, 2021·Pigment Cell & Melanoma Research·Hee Young KangMauro Picardo

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