To examine the epidemiology of oral cancer in England and Wales from 1901 to 1990 using trends in mortality and incidence rates. Data were obtained from OPCS archives for mortality and incidence of malignant neoplasia of the oral cavity (ICD 141, 143-146). Age-specific and age-standardised rates were calculated for both genders. Mortality data were available from 1901 but national incidence figures only commenced in 1962. Despite overall reductions for oral cancer in England and Wales during this century, significant increases in mortality and incidence have occurred in younger males during the last 30 years. These are associated with clear birth cohorts. No such cohort effects are apparent in females, despite similar though less pronounced trends. These results support similar studies in other parts of the UK and Europe. In the future there may be a substantial increase in the burden of new cases of oral cancer as birth cohorts with rising incidence rates enter age groups with higher disease frequencies. It is possible that raised alcohol consumption during the last 40 years may be responsible for the increases. This report reinforces the necessity to evaluate preventive programmes for oral cancer in the UK.
Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx and larynx
AlphaVbeta6 integrin promotes invasion of squamous carcinoma cells through up-regulation of matrix metalloproteinase-9
Immunoperoxidase detection of polycyclic aromatic hydrocarbon-DNA adducts in mouth floor and buccal mucosa cells of smokers and nonsmokers
Risk factors for squamous cell carcinoma of the oral cavity in young people--a comprehensive literature review
A new approach to pre-treatment assessment of the N0 neck in oral squamous cell carcinoma: the role of sentinel node biopsy and positron emission tomography
Need for appropriate written information for patients, with particular reference to head and neck cancer
Prognostic value of facilitative glucose transporter Glut-1 in oral squamous cell carcinomas treated by surgical resection; results of EORTC Translational Research Fund studies
The process of symptom appraisal: cognitive and emotional responses to detecting potentially malignant oral symptoms
A systematic review of case-control studies of human papillomavirus infection in laryngeal squamous cell carcinoma
Is the incidence of oral and pharyngeal cancer increasing in Finland? An epidemiological study of 17,383 cases in 1953-1999
Chemopreventive effect of bovine lactoferrin on 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male F344 rats
Opportunistic screening for oral cancer and precancer in general dental practice: results of a demonstration study
Development of the Bowman-Birk inhibitor for oral cancer chemoprevention and analysis of Neu immunohistochemical staining intensity with Bowman-Birk inhibitor concentrate treatment
Factors affecting the referral of potentially malignant lesions from primary dental care: a pilot study in South Yorkshire
GDPs' self-perceived confidence and anxiety in their clinical and communication skills used when screening for oral cancer: UK variations
Para-Clinical and Immunological Evaluation in Buerger's Disease as a Suspected Autoimmune Disease: Case Series.
Cancer Incidence & Mortality
Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.