The epidemiology of pain in depression

Human Psychopharmacology
Jean-Pierre Lépine, Mike Briley

Abstract

Over 75% of depressed patients in primary care complain of painful physical symptoms such as headache, stomach pain, neck and back pain as well as non-specific generalized pain. The presence of such symptoms predicts a greater severity and a less favourable outcome of depression with a poorer health-related quality of life. World Health Organization data obtained in primary care centres worldwide show that 22% of all primary care patients suffer from persistent debilitating pain and that these patients are four times more likely to have co-morbid anxiety or depressive disorder than pain-free primary care patients. Not unexpectedly, the risk of depression is greater when the pain is more diffuse, as indicated by the number of painful sites, and has a greater effect on the quality of life. Certain depressive symptoms, such as low energy and sleep disturbances, are commonly found in patients with co-morbid pain, whereas the opposite is true for symptoms such as guilt and loneliness. Increasingly, major depression is seen as being composed of psychological, somatic and painful physical symptoms. In order to achieve full sustained remission it is necessary to treat symptoms in all three of these areas. The area of painful physical s...Continue Reading

References

Apr 1, 1979·The British Journal of Psychiatry : the Journal of Mental Science·S A Montgomery, M Asberg
Mar 1, 1992·Journal of General Internal Medicine·P D GerberR D Whiting
Aug 1, 1992·Journal of Abnormal Psychology·P M Nicassio, K A Wallston
Mar 1, 1991·The Clinical Journal of Pain·D A FishbainH Rosomoff
Apr 1, 1985·The American Journal of Psychiatry·J I HudsonH G Pope
Dec 1, 1967·The British Journal of Social and Clinical Psychology·M Hamilton
Jul 1, 1982·The Journal of Nervous and Mental Disease·D BlumerT Roth
Dec 1, 1994·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·L von Knorring, L Ekselius
Jan 1, 1994·Psychotherapy and Psychosomatics·E N StenagerK Jensen
Aug 1, 1993·Psychological Medicine·S O MoldinH Akiskal
May 1, 1993·The American Journal of Psychiatry·L J KirmayerM J Yaffe
Jan 1, 1997·International Clinical Psychopharmacology·J P LépineA Tylee
Oct 1, 1996·Journal of Child and Adolescent Psychopharmacology·D S PineJ Brook
Nov 4, 2000·Psychopathology·E Corruble, J D Guelfi
May 10, 2002·The Journal of Clinical Psychiatry·Stephen M Stahl
Jan 7, 2003·Archives of General Psychiatry·Maurice M Ohayon, Alan F Schatzberg
Mar 17, 2004·Arthritis and Rheumatism·Lesley M ArnoldPaul E Keck

❮ Previous
Next ❯

Citations

Jan 27, 2010·Psychopharmacology·S Stevens NegusKenner C Rice
Jul 5, 2012·Journal of Neurology·A TruiniG Cruccu
Nov 10, 2011·Brain : a Journal of Neurology·David Borsook
Oct 25, 2008·Journal of Pediatric Psychology·Kate KeenanDara E Babinski
Sep 22, 2006·The Clinical Journal of Pain·Helen G M VossenRichel Lousberg
May 19, 2011·Spine·Xiaotong LiuHuiyun Xiang
Oct 11, 2012·Journal of Pain Research·Mark BernauerYang Zhao
Aug 31, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Ching-Hua LinCheng-Chung Chen
Apr 21, 2012·Dento Maxillo Facial Radiology·S L P C LopesS M de Almeida
Feb 27, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Emmeline A WatkinsBarbara P Yawn
Dec 12, 2012·Expert Opinion on Investigational Drugs·Chi-Un Pae
Feb 13, 2016·The Journal of Pain : Official Journal of the American Pain Society·Marco HermesdorfHeike Wersching
Apr 1, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Angela M DeVeaugh-GeissKurt Kroenke
Aug 21, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·David A FishbainJinrun Gao
Aug 28, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Veronika LeichtfriedWolfgang Schobersberger
Apr 1, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Barbara P YawnL Joseph Melton
Jun 5, 2012·Journal of Psychosomatic Research·Lana J WilliamsMichael Berk
Apr 17, 2012·Neuroscience Letters·Isabella MutschlerIrina A Strigo
Mar 20, 2012·The Journal of Pain : Official Journal of the American Pain Society·S Stevens NegusKenner C Rice
Nov 23, 2011·Archives of Gerontology and Geriatrics·N Kutay Ordu GokkayaUNKNOWN Geriatric Rehabilitation Research Group of Turkish Society of Physical Medicine and Rehabilitation
Apr 13, 2011·The Journal of Pain : Official Journal of the American Pain Society·Paul G GreenJon D Levine
Dec 15, 2010·Fertility and Sterility·Barbara Illowsky KarpPamela Stratton
Dec 9, 2009·Surgical Oncology·Ilaria SpoletiniGianfranco Spalletta
Jul 2, 2014·The Journal of Pain : Official Journal of the American Pain Society·Lannie LigthartDorret I Boomsma
Feb 17, 2009·Seminars in Arthritis and Rheumatism·Don L Goldenberg
May 12, 2009·Progress in Neurobiology·Jonathan SavitzWayne C Drevets
Nov 4, 2008·La Presse médicale·Antoine Pelissolo
Sep 27, 2008·Pharmacology, Biochemistry, and Behavior·Takayuki HayashiYoriko Kawakami
Aug 12, 2008·Journal of Affective Disorders·S KoeneE Morava
Jul 31, 2007·Journal of Psychosomatic Research·Mustafa M HusainMaurizio Fava
Apr 17, 2007·The Journal of Pain : Official Journal of the American Pain Society·David V Nelson
Dec 6, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Gary D Klasser, Reny de Leeuw
Feb 22, 2011·The British Journal of Clinical Psychology·Morgen A R KellyPaul A Pilkonis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.