The ESHRE PGD Consortium: 10 years of data collection

Human Reproduction Update
J C HarperG Harton

Abstract

Since it was established in 1997, the ESHRE PGD Consortium has been collecting data from international preimplantation genetic diagnosis (PGD) centres. Ten papers have been published, including data from January 1997 to December 2007. The data collection originally used a hard-copy format, then an excel database and finally a FileMaker Pro database. The indications are divided into five categories: PGD for chromosome abnormalities, sexing for X-linked disease, PGD for single gene defects, preimplantation genetic screening (PGS) and PGD for social sexing. The main end-points are pregnancy outcome and follow-up of deliveries. In data collection I, 16 centres contributed data, which increased to 57 centres by data X (average of 39 centres per data collection). These centres contributed data on over 27 000 cycles that reached oocyte retrieval. Of these cycles, 61% were for aneuploidy screening, 17% for single gene disorders, 16% for chromosomal abnormalities, 4% for sexing of X-linked disease and 2% for social sexing. Cumulatively, 5187 clinical pregnancies gave rise to 4140 deliveries and 5135 newborns (singletons: 3182, twins: 921, triplets: 37). In this paper, we present an overview of the first 10 years of PGD data, highlightin...Continue Reading

References

Feb 1, 1994·Current Biology : CB·J Stock, M Surette
Feb 1, 1996·Journal of Assisted Reproduction and Genetics·J C Harper
Dec 1, 2000·Human Reproduction·J GeraedtsUNKNOWN European Society of Human Reproduction and Embryology Preimplantation Genetic Diagnosis Consortium Steering Committee
Jan 5, 2002·Human Reproduction·UNKNOWN ESHRE PGD Consortium Steering Committee.
Aug 11, 2004·Fertility and Sterility·Yury VerlinskyAnver Kuliev
Sep 15, 2004·Fertility and Sterility·UNKNOWN Ethics Committee of the American Society for Reproductive Medicine
Nov 20, 2004·Human Reproduction·K SermonC De Die
Feb 12, 2005·Reproductive Biomedicine Online·Javid Gaziev, Guido Lucarelli
Apr 12, 2005·Reproductive Biomedicine Online·Joseph D Schulman, David S Karabinus
Dec 26, 2006·Expert Review of Molecular Diagnostics·Pamela Renwick, Caroline Mackie Ogilvie
Jul 6, 2007·The New England Journal of Medicine·Sebastiaan MastenbroekFulco van der Veen
Jul 22, 2008·Human Reproduction·V GoossensUNKNOWN European Society of Human Reproduction and Embryology PGD Consortium
Dec 17, 2008·Reproductive Biomedicine Online·Christophe BlockeelPaul Devroey
Dec 23, 2008·Prenatal Diagnosis·Claudia Spits, Karen Sermon
Jan 22, 2009·Human Reproduction·L WiltonJ C Harper
Dec 25, 2009·Human Reproduction·Joep GeraedtsAndreas Schmutzler
Oct 12, 2010·Genome Medicine·Martine De Rycke
Oct 23, 2010·Human Reproduction·G L HartonUNKNOWN European Society for Human Reproduction and Embryology (ESHRE) PGD Consortium/Embryology Special Interest Group
Oct 23, 2010·Human Reproduction·G HartonUNKNOWN European Society for Human Reproduction and Embryology (ESHRE) PGD Consortium
Oct 23, 2010·Human Reproduction·G L HartonUNKNOWN European Society for Human Reproduction and Embryology (ESHRE) PGD Consortium
Oct 23, 2010·Human Reproduction·G L HartonUNKNOWN European Society for Human Reproduction and Embryology (ESHRE) PGD Consortium
Oct 26, 2010·Fertility and Sterility·Cristina Gutiérrez-MateoSantiago Munné

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Citations

Apr 13, 2013·Human Reproduction·W DondorpK Diedrich
Feb 23, 2013·Current Opinion in Obstetrics & Gynecology·Stephen C Collins
Sep 4, 2013·Genome Medicine·Niels Van der AaThierry Voet
May 9, 2014·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Senthilkumar A NatesanAlan H Handyside
Jul 17, 2013·Archives of Gynecology and Obstetrics·Andreas G SchmutzlerNorbert Arnold
Jan 1, 2014·Journal of Clinical Medicine·Elsbeth DulConny van Ravenswaaij-Arts
Jan 1, 2014·Journal of Clinical Medicine·Gwendolyn P QuinnSusan T Vadaparampil
Dec 5, 2013·European Journal of Human Genetics : EJHG·Jos DreesenJoanne Traeger-Synodinos
May 30, 2014·Journal of Assisted Reproduction and Genetics·R Bautista-LlácerX Vendrell
May 29, 2014·Nature Reviews. Neurology·Ilan Tur-KaspaP Murali Doraiswamy
Jun 22, 2014·Gynécologie, obstétrique & fertilité·L AlterC Sifer
Dec 3, 2014·Journal de gynécologie, obstétrique et biologie de la reproduction·V GallotF Vialard
Mar 22, 2014·Orphanet Journal of Rare Diseases·Barbara W van PaassenMarianne de Visser
Aug 21, 2015·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Simone PaliniLuca Galluzzi
Aug 28, 2015·Human Fertility : Journal of the British Fertility Society·Virginia N BoltonJoyce C Harper
Aug 1, 2012·Expert Review of Molecular Diagnostics·Sioban B SenGupta, Joy D A Delhanty
Jan 1, 2014·Journal of Clinical Medicine·Ana Bustamante-AragonesMarta Rodriguez de Alba
Sep 24, 2014·Systems Biology in Reproductive Medicine·Claire Ann JonesRebecca Arthur
Dec 3, 2014·The Kaohsiung Journal of Medical Sciences·Levent SahinAyse Ender Yumru
Feb 5, 2014·Obstetrics and Gynecology Clinics of North America·Paul R Brezina, William G Kearns
Feb 5, 2014·Obstetrics and Gynecology Clinics of North America·Paul R Brezina, William H Kutteh
Aug 13, 2013·Reproductive Biomedicine Online·Markus MontagThomas Strowitzki
Oct 23, 2012·Gynécologie, obstétrique & fertilité·P Gosset
Nov 6, 2012·Reproductive Biomedicine Online·Jacques CohenMartin H Johnson
Aug 4, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Boran JiangSamuel S Chong
Jan 19, 2016·Reproductive Biomedicine Online·S B SenGuptaJ C Harper
Jul 16, 2014·Taiwanese Journal of Obstetrics & Gynecology·Chun-Kai ChenChyi-Long Lee
May 20, 2015·American Journal of Human Genetics·Masoud Zamani EstekiThierry Voet
Sep 19, 2015·Reproductive Biomedicine Online·Gheona AltarescuPaul Renbaum
Apr 25, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Hans Jakob Ingerslev, Johnny Hindkjaer
Mar 18, 2016·Journal of Assisted Reproduction and Genetics·Ashley W TiegsJames A Grifo

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