The Essential Oils of Rhaponticum carthamoides Hairy Roots and Roots of Soil-Grown Plants: Chemical Composition and Antimicrobial, Anti-Inflammatory, and Antioxidant Activities

Oxidative Medicine and Cellular Longevity
Ewa SkałaTomasz Śliwiński

Abstract

The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of Rhaponticum carthamoides and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the differences in the qualitative and quantitative composition. The sesquiterpene hydrocarbons (55-62%) dominated in both essential oils. The major compounds of HR essential oil were cyperene, 13-norcypera-1(5),11(12)-diene, and cadalene while aplotaxene, nardosina-1(10),11-diene, and dauca-4(11),8-diene dominated in SGR essential oil. Both essential oils showed antibacterial activity especially against Enterococcus faecalis (ATCC 29212) and Pseudomonas aeruginosa (ATCC 27853) (MIC value = 125 µg/mL). HR and SGR essential oils also decreased the expression of IL-1β, IL-6, and TNF-α and the ROS level in LPS-treatment astrocytes. This is the first report to describe the chemical composition of R. carthamoides essential oil from hairy roots, its protective effect against LPS-induced inflammation and ROS production in astrocytes, and its antimicrobial potential. The results show that R. carthamoides hairy roots may be a valuable source of the essential oil and may be ...Continue Reading

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Citations

Mar 7, 2018·BMC Complementary and Alternative Medicine·Habib MosbahBoulbaba Selmi
Jul 28, 2020·International Journal of Molecular Sciences·Przemysław SitarekTomasz Śliwiński
Jan 24, 2019·Oxidative Medicine and Cellular Longevity·Érica Martins de LavorJackson Roberto Guedes da Silva Almeida
Dec 16, 2020·Comprehensive Reviews in Food Science and Food Safety·Zizhan LiPangzhen Zhang

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