The establishment of embryonic axial properties in the nemertean, Cerebratulus lacteus

Developmental Biology
Jonathan Q Henry, Mark Q Martindale

Abstract

Experiments were performed to determine whether the first cleavage division plays a role in setting up the dorsoventral axis in embryos of the equal-cleaving nemertean Cerebratulus lacteus. Fertilized eggs were compressed to change the orientation of the first cleavage spindle, and thus the plane of the first cleavage division. One cell of the resulting two-celled embryos was then injected with lineage tracer to determine whether the first cleavage plane always maintains its normal relationships to the median and frontal planes or whether new relationships (and thus, novel cell lineages) could be created. Many of these compressed embryos gave rise to normal-appearing pilidium larvae in which the first cleavage plane had taken on various oblique angular relationships relative to the plane of bilateral symmetry and the dorsoventral axis of the larva. These findings indicate that the first cleavage plane can be dissociated from its normal relationships to these axial properties. Thus, the first cleavage division is not causally involved in the establishment of the dorsoventral and bilateral axes. We argue that the dorsoventral axis is specified prior to the first cleavage division.

Citations

May 12, 2011·Integrative and Comparative Biology·Cristina Grande
Dec 15, 2005·Zoology : Analysis of Complex Systems, ZACS·Gonzalo Giribet
Aug 23, 2018·Developmental Dynamics : an Official Publication of the American Association of Anatomists·C Cornelia OsborneJonathan Q Henry
May 26, 2005·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Claus Nielsen
Nov 6, 2020·Developmental Biology·Longjun Wu, J David Lambert

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