The Ethics of End-of-Trial Obligations in a Pediatric Malaria Vaccine Trial: The Perspectives of Stakeholders From Ghana and Tanzania

Journal of Empirical Research on Human Research Ethics : JERHRE
Claire Leonie WardBernice Elger

Abstract

This study explores stakeholder experiences and perspectives on end-of-trial obligations at the close of a phase II/III Pediatric Malaria Vaccine Trial (PMVT) [GSK/PATH-MVI RTS, S) (NCT00866619]. We conducted 52 key informant interviews with major stakeholders of an international multicentre PMVT in Ghana and Tanzania. The responses fell into four main themes: (a) Communicating End-of-Trial, (b) Maintaining Health Care Services, (c) Dissemination of Results, and (d) Post-Trial Access. Interviewee responses shared important practical experiences and insights that complement current thinking in the literature on research ethics guidance: (a) accompany end-of-trial communication with information on personal and family health care responsibilities, (b) establish public health indicators to measure the impact of research on a health care system,

References

Apr 1, 2005·The Hastings Center Report·Alex John London
Oct 14, 2006·Developing World Bioethics·Fatima Alvarez-Castillo, Dafna Feinholz
Jul 8, 2008·Lancet·Alex John London, Jonathan Kimmelman
Oct 22, 2013·JAMA : the Journal of the American Medical Association·UNKNOWN World Medical Association
Jul 6, 2014·BMJ : British Medical Journal·Rafael Dal-RéDavid Wendler
Jul 22, 2015·Developing World Bioethics·Bridget Haire, Christopher Jordens
Mar 10, 2016·Malaria Journal·Idda RomoreSalim Abdulla
Apr 3, 2016·Developing World Bioethics·Daniel J Hurst
May 20, 2016·Journal of Medical Ethics·Emily Largent
May 25, 2016·The American Journal of Bioethics : AJOB·Bridget Gabrielle Haire
Dec 27, 2016·Vaccine·Allan Saul, Katherine L O'Brien
Jan 26, 2017·Human Vaccines & Immunotherapeutics·Malcolm Molyneux
Nov 29, 2017·Journal of Empirical Research on Human Research Ethics : JERHRE·Claire Leonie WardBernice Elger

❮ Previous
Next ❯

Citations

Oct 10, 2018·Journal of Empirical Research on Human Research Ethics : JERHRE·Patrick T WilsonMarilyn C Morris

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antimalarial Agents (ASM)

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.

Antimalarial Agents

Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.