The evaluation and treatment implications of isolated pulmonary nodules in patients with a recent history of breast cancer

American Journal of Surgery
Eugene Y ChangNathalie Johnson

Abstract

Breast cancer patients with pulmonary lesions are often assumed to have metastatic disease and treated palliatively. We evaluated the proportion of these patients who actually have primary lung tumor (PLT) and assessed their outcome. We performed a 10-year retrospective review of the cancer registry in a community hospital system. Among 54 breast cancer patients with pulmonary nodules, biopsy was pursued in 30. Although metastatic breast cancer (MBC) was presumed in 24, biopsy showed MBC in 9 patients and PLT in 21. The two groups differed in age, stage, breast tumor size, nodal involvement, and estrogen receptor (ER) positivity. However, no variable excluded the possibility of PLT. Of those with PLT, 11 had early-stage lung disease; 9 underwent curative resection. Women with breast cancer and 1 or more pulmonary lesions without evidence of other metastatic disease require work-up of pulmonary lesions. Aggressive evaluation can afford treatment of lung cancer and impact survival.

References

Feb 1, 1975·Annals of Surgery·W G Cahan, E B Castro
Nov 1, 1992·Archives of Surgery·E D StarenL P Faber
Aug 11, 1992·The Annals of Thoracic Surgery·L A LanzaJ B Putnam
Dec 1, 1994·The Annals of Thoracic Surgery·M L McDonaldP C Pairolero
Mar 22, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·J B SeoM Y Kim
Mar 12, 2005·CA: a Cancer Journal for Clinicians·D Max ParkinPaola Pisani
Apr 28, 2005·The Annals of Thoracic Surgery·Fumihiro TanakaHiromi Wada

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Citations

Sep 15, 2009·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M TennisP G Shields
Jun 15, 2007·Seminars in Oncology·David I Sternberg, Joshua R Sonett
Jul 4, 2007·Surgical Oncology Clinics of North America·Todd L Demmy, Kelli Bullard Dunn
Nov 18, 2014·Case Reports in Pulmonology·Preetam AcharyaRahul Magazine
May 30, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Kuang-Wen OuJyh-Cherng Yu
Aug 19, 2009·American Journal of Clinical Pathology·Robin T Vollmer
Dec 20, 2008·American Journal of Clinical Pathology·Jonathon HerbstAlberto Marchevsky
Jul 24, 2014·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hee Jung SuhKyungran Ko
Feb 22, 2018·Diagnostic Cytopathology·Laleh HakimaRouzan G Karabakhtsian

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