The evaluation of neutrophil-lymphocyte ratio in children with asthma

Allergologia et immunopathologia
Mahmut Dogru, Rahime Gul Yesiltepe Mutlu

Abstract

Neutrophil-lymphocyte ratio (NLR) is a test used to evaluate the systemic inflammation. There is little knowledge about the neutrophil-lymphocyte ratio in asthmatics. In our study, we aimed to evaluate NLR and to assess its relationship with clinical parameters in children with asthma. Four hundred and sixty-nine children diagnosed with asthma and followed in our hospital were included in the study. The control group included 170 children with no evidence of allergic disease (i.e. asthma, allergic rhinitis, eczema) or infection. Skin prick tests were performed using the same antigens for all patients. The immunoglobulin E levels and complete blood count were measured. There was no difference between the groups with regard to gender and age. Mean NLR was 2.07±1.41 in the study group and 1.77±1.71 in the control group. The difference was statistically significant (p=0.043). There was no statistically significant difference between NLR and gender, familial atopy, exposure to smoke, sensitivity to allergens (p>0.05). While mean NLR was weakly positively correlated with number of hospitalisations (r: 0.216; p: 0.012), the percentage of eosinophils was weakly negatively correlated with NLR (r: -0.195; p: 0.001). Mean NLR is higher in...Continue Reading

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Citations

May 20, 2017·International Ophthalmology·Bengi Ece KurtulPinar Altiaylik Ozer
Sep 22, 2019·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Ayşe Enise GökerYavuz Uyar
Mar 18, 2017·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Ying Jiang, Wencong Ma
Jun 13, 2021·Clinica Chimica Acta; International Journal of Clinical Chemistry·Susan MikkelsenChristian Erikstrup

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