The evaluation of the clinical effect of topical St Johns wort (Hypericum perforatum L.) in plaque type psoriasis vulgaris: a pilot study

The Australasian Journal of Dermatology
Parvaneh NajafizadehReza Chalangari

Abstract

In this case series, ten patients with plaque-type psoriasis were treated with Hypericum perforatum ointment. The hypericum ointment was applied to one side of each patient's body and the vehicle to the opposite side twice daily for 4 weeks in a single blinded manner. Modified psoriasis area severity index (PASI) scores were significantly lowered where the formulated ointment had been applied. In determining PASI scores, three factors, erythema, scaling and thickness, were evaluated; all were significantly lower where the formulated ointment had been applied (P = 0.01, P = 0.004, P = 0.04). Hypericum perforatum ointment applied twice daily may be effective in reducing PASI scores in mild plaque-type psoriasis, however, further larger studies need be conducted to achieve a more conclusive result.

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Citations

May 28, 2019·BMC Veterinary Research·Milena TreschMichael Walkenhorst
May 30, 2019·International Journal of Molecular Sciences·Tse-Hung HuangJia-You Fang
Aug 8, 2017·Annals of Medicine·Dongmei WangChuanjian Lu
Feb 13, 2020·Biomedicines·Julia HoffmannUte Wölfle
Mar 16, 2017·American Journal of Clinical Dermatology·Benjamin FarahnikRaja K Sivamani
Oct 13, 2017·Journal of Postgraduate Medicine·D M Thappa, M Malathi
Apr 4, 2021·Biomolecules·Fabian GendrischUte Wölfle

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