The evaluation of the diet/disease relation in the EPIC study: considerations for the calibration and the disease models

International Journal of Epidemiology
P FerrariE Riboli

Abstract

International multicentre studies on diet and cancer are relatively new in epidemiological research. They offer a series of challenging methodological issues for the evaluation of the association between dietary exposure and disease outcomes, which can both be quite heterogeneous across different geographical regions. This requires considerable work to standardize dietary measurements at the food and the nutrient levels. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), a calibration study was set up to express individual dietary intakes according to the same reference scale. A linear regression calibration model was used to correct the association between diet and disease for measurement errors in dietary exposures. In the present work, we describe an approach for analysing the EPIC data, using as an example the evaluation of the association between fish intake and colorectal cancer incidence. Sex- and country-specific attenuation factors ranged from 0.083 to 0.784, with values overall higher for men compared with women. Hazard ratio estimates of colorectal cancer for a 10 g/day increase in fish intake were 0.97 [95% confidence interval (CI): 0.95-0.99] and 0.93 (0.88-0.98), before and after calib...Continue Reading

References

Dec 1, 1992·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E Riboli
Jul 1, 1967·Journal of Chronic Diseases·J TruettW Kannel
Sep 1, 1995·American Journal of Epidemiology·R KaaksW van Staveren
Jan 1, 1997·American Journal of Epidemiology·E L KornD Midthune
Apr 1, 1997·The American Journal of Clinical Nutrition·W C WillettL H Kushi
Dec 31, 1997·American Journal of Epidemiology·V KipnisS Wacholder
Sep 1, 2000·American Journal of Epidemiology·P A CarneyR Ballard-Barbash
May 23, 2001·International Journal of Epidemiology·W Willett
Mar 14, 2003·Public Health Nutrition·Victor KipnisRaymond J Carroll
Jul 2, 2003·American Journal of Epidemiology·Victor KipnisRaymond J Carroll
Jul 30, 2003·Lancet·Sheila A BinghamNicholas Day
Dec 19, 2003·International Journal of Epidemiology·Martyn Plummer, Rudolf Kaaks
Aug 31, 2004·International Journal of Epidemiology·N E DayN J Wareham
Aug 31, 2004·International Journal of Epidemiology·Rupert W JakesNicholas J Wareham
Oct 7, 2004·American Journal of Epidemiology·Pietro FerrariUNKNOWN European Prospective Investigation into Cancer and Nutrition study
Dec 8, 2004·Statistics in Medicine·Anne C M Thiébaut, Jacques Bénichou
Jun 16, 2005·Journal of the National Cancer Institute·Teresa NoratElio Riboli
Apr 21, 2006·American Journal of Epidemiology·Stephanie A Smith-WarnerDavid J Hunter

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Citations

Nov 2, 2012·European Journal of Nutrition·Pietro FerrariNadia Slimani
Sep 11, 2009·The British Journal of Nutrition·Lluís Serra-Majem
Dec 14, 2011·The British Journal of Nutrition·Marianne U JakobsenKim Overvad
Jun 22, 2012·The British Journal of Nutrition·Marianne U JakobsenKim Overvad
Nov 6, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·V FedirkoM Jenab
Jan 20, 2011·European Heart Journal·Francesca L CroweUNKNOWN European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart Study Collaborators
Apr 3, 2008·International Journal of Epidemiology·Donna Spiegelman
Jul 9, 2011·International Journal of Epidemiology·George C M Siontis, John P A Ioannidis
Apr 8, 2010·Journal of the National Cancer Institute·Paolo BoffettaAntonia Trichopoulou
Oct 4, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Annika SteffenHeiner Boeing
May 8, 2010·Journal of the American Statistical Association·Raymond J CarrollPeter Hall
Apr 11, 2014·Journal of the National Cancer Institute·Sabina SieriVittorio Krogh
Apr 13, 2013·European Journal of Epidemiology·Christina BamiaAntonia Trichopoulou
Aug 27, 2014·European Journal of Epidemiology·Max LeendersH Bas Bueno-de-Mesquita
Dec 17, 2014·Journal of the National Cancer Institute·J de BatlleI Romieu
Apr 20, 2013·American Journal of Epidemiology·Max LeendersH Bas Bueno-de-Mesquita
Jun 13, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nirmala Bhoo-PathyH Bas Bueno-De-Mesquita
Sep 27, 2014·International Journal of Cancer. Journal International Du Cancer·Sabine RohrmannHeiner Boeing
Dec 25, 2008·International Journal of Cancer. Journal International Du Cancer·Alina VrielingH Bas Bueno-de-Mesquita
May 23, 2012·International Journal of Cancer. Journal International Du Cancer·Sabine RohrmannH Bas Bueno-de-Mesquita
May 24, 2012·International Journal of Cancer. Journal International Du Cancer·Naomi E AllenElio Riboli
Aug 18, 2010·International Journal of Cancer. Journal International Du Cancer·Martine M RosElio Riboli
Nov 28, 2012·International Journal of Cancer. Journal International Du Cancer·G BucklandE Riboli
Mar 23, 2012·International Journal of Cancer. Journal International Du Cancer·Esther Molina-MontesBas Bueno-de-Mesquita
Jul 21, 2009·International Journal of Cancer. Journal International Du Cancer·Frederike L BüchnerElio Riboli
Oct 31, 2009·International Journal of Cancer. Journal International Du Cancer·Anthony B Miller, Jakob Linseisen
Jun 18, 2015·International Journal of Cancer. Journal International Du Cancer·Talita Duarte-SallesMazda Jenab
Aug 7, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Martine M RosElio Riboli

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