The evolution of foot-and-mouth disease virus: impacts of recombination and selection

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Nicole Lewis-RogersKeith A Crandall

Abstract

Foot-and-mouth disease virus is an economically important animal virus that exhibits extensive genetic and antigenic heterogeneity. To examine the evolutionary forces that have influenced the population dynamics of foot-and-mouth disease virus, individual genes and the coding genomes for the Eurasian (Asia1, A, C, and O) serotypes were examined for phylogenetic relationships, recombination, genetic diversity and selection. Our analyses demonstrate that paraphyletic relationships among serotypes are not as prevalent as previously proposed and suggest that convergent evolution might be obscuring phylogenetic relationships. We provide evidence that identification of recombinant sequences and recombination breakpoint patterns among and within serotypes are heavily dependent on the level of genetic diversity and convergent characters present in a particular data set as well as the methods used to detect recombination. Here, we also investigate the impact of adaptive positive selection on the capsid proteins and the non-structural genes 2B, 2C, 3A, and 3Cpro to identify genome regions involved in genetic diversity and antigenic variation. Two different categories of positive selection at the amino acid level were examined; conservati...Continue Reading

References

Feb 1, 1992·Journal of Molecular Evolution·J M Smith
Jun 1, 1973·The Journal of Clinical Endocrinology and Metabolism·L ShenkmanC S Hollander
Jan 1, 1995·Annual Review of Biochemistry·M T Heemels, H Ploegh
Jun 24, 1997·Proceedings of the National Academy of Sciences of the United States of America·M A MartínezE Domingo
Nov 21, 1997·Computer Applications in the Biosciences : CABIOS·Z Yang
Dec 31, 1997·Genetics·J J BullI J Molineux
Apr 30, 1998·Genetics·J W DrakeJ F Crow
Jan 27, 1999·Bioinformatics·D Posada, K A Crandall
Jun 11, 1999·Journal of Virology·P Simmonds, D B Smith
Sep 11, 1999·Science·R MirallesS F Elena
Nov 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·J W Drake, J J Holland
May 16, 2001·Science·E BaranowskiE Domingo
May 24, 2001·Molecular Biology and Evolution·G M JenkinsE C Holmes
Aug 4, 2001·Trends in Genetics : TIG·A R Samuel, N J Knowles
Nov 22, 2001·Proceedings of the National Academy of Sciences of the United States of America·D Posada, K A Crandall
Jan 12, 2002·Journal of Molecular Biology·Carmen M Ruíz-JaraboEsteban Domingo
Apr 19, 2002·Molecular Biology and Evolution·David Posada
Mar 14, 2003·Journal of Virology·Edward C Holmes
Mar 26, 2003·Bioinformatics·Steve WoolleyDavid A McClellan
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Oct 8, 2003·Systematic Biology·Stéphane Guindon, Olivier Gascuel
Oct 15, 2003·Journal of Molecular Biology·Carmen M Ruiz-JaraboEsteban Domingo
Dec 12, 2003·Bioinformatics·Julio RozasRicardo Rozas
Jan 17, 2004·Science·Bryan T GrenfellEdward C Holmes
Mar 23, 2004·Nucleic Acids Research·Robert C Edgar
Apr 16, 2004·Clinical Microbiology Reviews·Marvin J Grubman, Barry Baxt
Sep 21, 2004·Bioinformatics·D P MartinD Posada
Jan 22, 2005·The Journal of General Virology·M Steven ObersteMark A Pallansch
Feb 4, 2005·Molecular Biology and Evolution·Ziheng YangRasmus Nielsen
Apr 29, 2005·Journal of Virology·C CarrilloD L Rock

❮ Previous
Next ❯

Citations

Mar 31, 2011·Molecules and Cells·Sook Hee YoonHeebal Kim
Apr 29, 2010·Veterinary Research Communications·Jian-Hua ZhouYong-Sheng Liu
Feb 3, 2009·Molecular Biology and Evolution·Nicole Lewis-RogersKeith A Crandall
Aug 10, 2011·Experimental & Molecular Medicine·Insung AhnHyeon Seok Son
Oct 20, 2009·Molecular Phylogenetics and Evolution·Nicole Lewis-Rogers, Keith A Crandall
Apr 1, 2011·Transboundary and Emerging Diseases·U WaheedN J Knowles
Aug 2, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Jian-Hua ZhouYong-Sheng Liu
May 7, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Saravanan SubramaniamBramhadev Pattnaik
Dec 26, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Sabenzia N WekesaHans R Siegismund
Dec 12, 2012·International Journal for Parasitology·Katie L SealeyScott P Lawton
May 28, 2013·Molecular Phylogenetics and Evolution·Kristi M WestoverMatthew Neal
Apr 26, 2018·Viruses·Luca FerrettiPaolo Ribeca
Apr 19, 2013·Clinical and Experimental Vaccine Research·Jong-Hyeon Park
Nov 24, 2019·Transboundary and Emerging Diseases·Syed M JamalGraham J Belsham
Apr 26, 2019·PloS One·Jonathan ArztCarolina Stenfeldt
Apr 30, 2021·Transboundary and Emerging Diseases·Syed M JamalGraham J Belsham

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Jessica N Cooke, Kristi M Westover
The Journal of General Virology
A L JacksonD T Haydon
© 2022 Meta ULC. All rights reserved