PMID: 107686Jan 1, 1978

The evolution of sexual reproduction as a repair mechanism. Part I. A model for self-repair and its biological implications

Acta Biotheoretica
I Walker

Abstract

The theory is presented that the sexual process is a repair mechanism which maintains redundancy within the sub-structure of hierarchical, self-reproducing organisms. In order to keep the problems within mathematically tractable limits (see Part II), a simple model is introduced: a wheel with 6 spokes, 3 of them vital and 3 redundant, symbolizes the individual (cell or organism). Random accidents destroy spokes; the wheels replicate at regular cycles and engage periodically in pairing and repair phases during which missing spokes are copy-reproduced along the intact spokes of the partner wheel. The hierarchical structure of such a system is analysed and an 'autonomous unit' is defined: this is the unit of minimal hierarchical complexity which is capable of perpetuating autonomously all higher and all lower levels of the hierarchy; this is the central unit of selection. Four basic, physical parameters are isolated which determine the essential features of any eucaryotic life cycle: 1. The number of levels of the hierarchy (unicellular, multicellular, colonial, etc.); 2. the relation between the phases of replication (asexual generations) and repair (sexual generations); 3. the duration of potential repair (haplo-diplo-phase); 4....Continue Reading

References

Jan 1, 1976·Acta Biotheoretica·I Walker, R M Williams
Jan 1, 1976·Acta Biotheoretica·I Walker
Jan 1, 1974·Cold Spring Harbor Symposia on Quantitative Biology·E H DavidsonR J Britten
Jan 1, 1974·Cold Spring Harbor Symposia on Quantitative Biology·C A ThomasB H Zimm
Jan 1, 1972·Acta Biotheoretica·I Walker
Jun 1, 1973·Journal of Theoretical Biology·G C Williams, J B Mitton
Jul 28, 1970·Journal of Molecular Biology·T J Kelly, H O Smith
Sep 1, 1970·Journal of Theoretical Biology·M Conrad, H H Pattee

Citations

Jun 1, 1990·Acta Biotheoretica·A Steiner, I Walker
Aug 15, 1983·Experientia·I Walker
Dec 1, 1981·Mechanisms of Ageing and Development·Z A Medvedev
May 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·W D HamiltonR Tanese
Jan 1, 1994·International Journal of Aging & Human Development·B C Hayes, A VandenHeuvel
Jan 1, 1983·Journal of Sex & Marital Therapy·M F Schwartz, W H Masters

Related Concepts

Metazoa
Chromosomes
Base Excision Repair
Biological Evolution
M Phase, Meiotic
Recombination, Genetic
Reproduction

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