The evolution of the nuclear receptor superfamily

Essays in Biochemistry
H EscrivaVincent Laudet

Abstract

Nuclear receptors form a superfamily of ligand-activated transcription factors implicated in various physiological functions from development to homoeostasis. Nuclear receptors share a common evolutionary history revealed by their conserved structure and by their high degree of sequence conservation. Here we review the latest advances on the evolution of nuclear receptors by addressing the following questions. What is known about the appearance and diversification of nuclear hormone receptors? How did their different functional characteristics evolve? What can we infer from the analysis of complete genomes? In summary, the study of the evolution of nuclear receptors will be very important not only for understanding their functions in vivo but also for obtaining insights into the evolution of animal genomes as a whole.

Citations

Nov 3, 2004·Nature Reviews. Drug Discovery·Hinrich GronemeyerVincent Laudet
Oct 14, 2005·Toxicological Sciences : an Official Journal of the Society of Toxicology·Edwin SonneveldBart van der Burg
Aug 2, 2007·Molecular Endocrinology·Sharmistha DasHerbert H Samuels
Sep 6, 2007·Journal of Cellular Biochemistry·Giuseppe Carruba
Feb 28, 2007·Molecular and Cellular Biology·Chun-Song YangBryce M Paschal
Mar 28, 2013·International Journal of Endocrinology·Monika Puzianowska-KuznickaJacek Polosak
Oct 21, 2016·Expert Opinion on Therapeutic Patents·Miguel A MaestroCarsten Carlberg
Aug 28, 2018·Nuclear Receptor Research·Gisela I MazairaMario D Galigniana
Aug 30, 2005·Endocrine Reviews·David J MulhollandColleen C Nelson
Jan 31, 2007·Annals of the New York Academy of Sciences·Giuseppe Carruba
Oct 6, 2007·Critical Reviews in Biochemistry and Molecular Biology·Suzannah RutherfordBillie J Swalla
Jul 2, 2010·Annual Review of Cell and Developmental Biology·Shelley LumbaPeter McCourt
Dec 6, 2008·The Journal of Biological Chemistry·Jitendra K ThakurAnders M Näär
Jun 11, 2011·Acta Orthopaedica·Darja Obradovic Wagner, Per Aspenberg
Mar 1, 2017·Cold Spring Harbor Perspectives in Medicine·Barbara KuprChristoph Handschin
Jan 31, 2018·Journal of the Endocrine Society·Rafah MackehTomoshige Kino
Jul 30, 2005·Molecular Endocrinology·Ronald N MargolisUNKNOWN NURSA Atlas Consortium
Apr 12, 2007·Journal of Biosciences·Raghu Prasad Rao MetpallyRamanathan Sowdhamini
Apr 22, 2009·Nuclear Receptor Signaling·Manuel MarkPierre Chambon
Oct 25, 2011·Annual Review of Entomology·Susan E FahrbachRodrigo A Velarde
May 6, 2010·Journal of Molecular Evolution·Christophe M R LeMoineChristopher D Moyes
Feb 9, 2010·Nucleic Acids Research·Tomasz KrusińskiPiotr Dobryszycki
Aug 23, 2011·Genome Biology and Evolution·Ricard AlbalatMichael Schubert
Oct 5, 2010·Reproductive Sciences·Sam MesianoErrol R Norwitz
Nov 20, 2014·Human Reproduction Update·Bansari PatelSam Mesiano
Mar 1, 2007·Animal : an International Journal of Animal Bioscience·K CosteV Sapin
May 3, 2012·Journal of Neurochemistry·Natalia M GalignianaMario D Galigniana

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