The Evolving Role of Multivitamin/Multimineral Supplement Use among Adults in the Age of Personalized Nutrition

Nutrients
Jeffrey B BlumbergCornelia M Ulrich

Abstract

Micronutrient deficiencies occur in segments of the adult population in the United States. Multivitamin/multimineral supplements (MVMS) are widely used by this population, which reduces inadequacies in micronutrient intake, but the potential for exceeding tolerable upper intake levels in others should be considered. There are concerns associated with the excessive intake of certain nutrients, particularly folic acid, and potential untoward consequences. The advent of nutrigenomics and the enhanced ability to directly study the interactions between nutrition and genetic variants and expression will allow for the conduct of more targeted studies with specific endpoints and may ultimately lead to progress in the field of personalized nutrition. The role of MVMS in health maintenance and chronic disease prevention remains controversial. Conducting studies in this area has been hampered by, among other factors, inconsistent definitions of MVMS, ranging from as few as three vitamins to broad-spectrum products containing more than two dozen vitamins and minerals. Results from some observational studies and large-scale, randomized, controlled trials suggest that MVMS may reduce the risk of some forms of cancer and, potentially, cardiov...Continue Reading

References

Oct 4, 1995·JAMA : the Journal of the American Medical Association·C J BousheyA G Motulsky
Jul 26, 2000·American Journal of Epidemiology·M L WatkinsC W Heath
Feb 15, 2002·The New England Journal of Medicine·Sudha SeshadriPhilip A Wolf
Aug 7, 2002·The Journal of Nutrition·Sang-Woon Choi, Joel B Mason
Oct 26, 2002·JAMA : the Journal of the American Medical Association·UNKNOWN Homocysteine Studies Collaboration
Nov 11, 2003·The Journal of Nutrition·Young-In Kim
Aug 3, 2004·American Journal of Epidemiology·Kathy RadimerMary Frances Picciano
Nov 13, 2004·The Journal of Nutritional Biochemistry·Y I Kim
Jun 7, 2007·JAMA : the Journal of the American Medical Association·Bernard F ColeUNKNOWN Polyp Prevention Study Group
Feb 11, 2009·Archives of Internal Medicine·Marian L NeuhouserRoss L Prentice
Mar 12, 2009·Journal of the National Cancer Institute·Jane C FigueiredoJohn A Baron
Aug 28, 2009·The Journal of Nutrition·Sarah E BelisleSimin Nikbin Meydani
Dec 29, 2009·Cancer Causes & Control : CCC·Jane C FigueiredoRobert W Haile
Feb 10, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Y LiC H Sun
Jul 10, 2010·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·A Joan LevineRobert W Haile
Sep 24, 2010·The American Journal of Clinical Nutrition·Susanne RautiainenAlicja Wolk
Dec 24, 2010·The Journal of Nutrition·Regan L BaileyMary Frances Picciano
Feb 24, 2011·American Journal of Epidemiology·Song-Yi ParkLaurence N Kolonel
Mar 25, 2011·Journal of Nutrigenetics and Nutrigenomics·Cindy D Davis, John A Milner
Jun 1, 2011·Journal of Nutrigenetics and Nutrigenomics·Michael FenechRichard Head
Jul 15, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Marian L NeuhouserCornelia M Ulrich
Aug 26, 2011·The Journal of Nutrition·Victor L FulgoniJohanna Dwyer
Oct 1, 2011·The American Journal of Clinical Nutrition·Regan L BaileyJohanna T Dwyer
Jan 6, 2012·The American Journal of Clinical Nutrition·Jeongseon KimYoon-Ok Ahn
Jun 20, 2012·Journal of the Academy of Nutrition and Dietetics·Regan Lucas BaileyJohanna T Dwyer
Aug 8, 2012·Epigenetics : Official Journal of the DNA Methylation Society·Cornelia M UlrichJean-Pierre J Issa
Nov 3, 2012·JAMA : the Journal of the American Medical Association·Howard D SessoJ Michael Gaziano
Nov 20, 2012·JAMA : the Journal of the American Medical Association·J Michael GazianoJulie E Buring
Nov 28, 2012·Journal of the American Geriatrics Society·Rebecca C RossomKaren L Margolis
Dec 21, 2012·The American Journal of Clinical Nutrition·Helen MacphersonMatthew P Pase
Jan 29, 2013·Lancet·Joshua W Miller, Cornelia M Ulrich
Feb 1, 2013·The Journal of Nutrition·Amy M BranumBarbara J Singer

❮ Previous
Next ❯

Citations

Jun 22, 2019·JAMA Network Open·Regan L BaileyPatrick M Catalano
Dec 19, 2019·Nutrients·Rebecca W PascualGary D Foster
Dec 7, 2018·Critical Reviews in Food Science and Nutrition·Dieuwertje E KokEllen Kampman
Oct 17, 2018·Proceedings of the National Academy of Sciences of the United States of America·Bruce N Ames
Apr 28, 2020·The Cochrane Database of Systematic Reviews·Zahra Ali PadhaniZulfiqar A Bhutta
Dec 11, 2019·The Pharmacogenomics Journal·Arun RadhakrishnanNikhitha K Shanmukhan
Feb 11, 2021·The American Journal of Clinical Nutrition·Prasad P DevarshiSusan Hazels Mitmesser
Feb 2, 2021·Gastroenterology Clinics of North America·Gerard E MullinAlyssa M Parian
Jun 3, 2021·International Journal of Molecular Sciences·Paul ClaytonRuchitha Venkatesh
Nov 19, 2021·The Cochrane Database of Systematic Reviews·Zahra Ali PadhaniZulfiqar A Bhutta

❮ Previous
Next ❯

Software Mentioned

COSMOS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.