PMID: 8938431Nov 1, 1996Paper

The exon structure of the mouse Sc1 gene is very similar to the mouse Sparc gene

Genome Research
P J McKinnonR F Margolskee

Abstract

Sc1 and Sparc are two extracellular proteins sharing similarity in their carboxyl terminus, with 63% identity over a 232-amino-acid region. We have cloned and mapped the genomic locus of mouse Sc1. The mouse Sc1 gene contains 11 exons spanning approximately 35 kb of DNA. The genomic structure (exon/intron boundaries) of Sc1 exons 6 to exon 11 is identical to those of the similar portion of the Sparc gene. This suggests that Sc1 and Sparc originated from a common ancestral gene. Using fluorescence in situ hybridization analysis, Sc1 was localized to band 5E4 of mouse chromosome 5.

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Citations

Dec 28, 1999·Molecular and Cellular Biology·P J McKinnonR F Margolskee
Feb 26, 1999·Leukemia & Lymphoma·K Oritani, P W Kincade
Nov 24, 1999·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Q Yan, E H Sage
Mar 19, 2003·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Qi YanE Helene Sage
Jun 24, 2004·Journal of Cellular Biochemistry·Paul E Framson, E Helene Sage

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