The Expanding Spectrum of Ligands for Leukocyte Ig-like Receptors

The Journal of Immunology : Official Journal of the American Association of Immunologists
Deborah N Burshtyn, Chris Morcos

Abstract

The human leukocyte Ig-like receptor family is part of the paired receptor system. The receptors are widely expressed by various immune cells, and new functions continue to emerge. Understanding the range of functions of the receptors is of general interest because several types of pathogens exploit the receptors and genetic diversity of the receptors has been linked to various autoimmune diseases. Class I major histocompatibility molecules were the first ligands appreciated for these receptors, but the types of ligands identified over the last several years are quite diverse, including intact pathogens, immune-modulatory proteins, and molecules normally found within the CNS. This review focuses on the types of ligands described to date, how the individual receptors bind to several distinct types of ligands, and the known functional consequences of those interactions.

References

Feb 13, 2001·European Journal of Immunology·E J LepinC A O'Callaghan
Nov 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·R L AllenM J Wilson
Sep 6, 2002·Journal of Immunological Methods·David S J AllanAndrew J McMichael
Jul 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Mitsunori ShiroishiKatsumi Maenaka
Apr 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Daniele SaverinoErmanno Ciccone
May 17, 2005·Nature Immunology·Jessica A HamermanLewis L Lanier
Jun 2, 2005·Nature Reviews. Immunology·John R Rodgers, Richard G Cook
Oct 8, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Sheryl E Kirwan, Deborah N Burshtyn
May 6, 2006·The Journal of Biological Chemistry·Mitsunori ShiroishiKatsumi Maenaka
Mar 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Masafumi NakayamaAlan Aderem
Mar 21, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Virginie Prod'hommePeter Tomasec
Apr 29, 2008·American Journal of Human Genetics·Kouyuki HirayasuToshio Yabe
May 20, 2008·Human Immunology·Chih-Chao ChangE Rodica Vasilescu
Sep 5, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Ikuko ToriiHiromi Kubagawa
Sep 20, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yu MoriToshiyuki Takai
Nov 8, 2008·Science·Jasvinder K AtwalMarc Tessier-Lavigne
Jan 7, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Demin LiXiao-Ning Xu
Jul 1, 2009·The Journal of Experimental Medicine·Wei CaoYong-Jun Liu
Jul 6, 2010·Human Immunology·Chelsea L DavidsonDeborah N Burshtyn
Jan 29, 2011·The Journal of Immunology : Official Journal of the American Association of Immunologists·Des C JonesRachel L Allen
Mar 19, 2011·Developmental and Comparative Immunology·Benjamin C MontgomeryJames L Stafford
Nov 22, 2011·Neurochemical Research·Xiaofeng CaiJian Ye
May 18, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Joanna GilesSimon Kollnberger
Nov 16, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Masafumi NakayamaKouetsu Ogasawara
Aug 6, 2013·Molecular Immunology·Jacqueline ShawSimon Kollnberger

❮ Previous
Next ❯

Citations

Aug 10, 2016·Frontiers in Immunology·Laura Emily Hudson, Rachel Louise Allen
Jun 30, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Aeryon KimXin Yu
Jun 30, 2019·The Journal of Biological Chemistry·Felix A DeussRichard Berry
Nov 7, 2019·The Journal of Immunology : Official Journal of the American Association of Immunologists·Kimiko KurokiKatsumi Maenaka
Apr 24, 2020·The Journal of Immunology : Official Journal of the American Association of Immunologists·Kang YuDeborah N Burshtyn
Feb 27, 2020·Seminars in Immunopathology·Katharina RöltgenCharlotte Avanzi
Mar 13, 2018·The Journal of Clinical Investigation·Kang YuDeborah N Burshtyn
Oct 16, 2019·Cellular & Molecular Immunology·Kyohei Nakamura, Mark J Smyth
Nov 18, 2020·Molecular Therapy. Methods & Clinical Development·Narjes Saheb Sharif-AskariRabih Halwani

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.