The expression of human beta2-microglobulin on human spermatozoa

European Journal of Immunology
M FellousC Tonnelle

Abstract

The expression of human beta2-microglobulin was detected on human spermatozoa from 7 donors using a cytotoxicity assay and indirect immunofluorescence. Inhibition experiments using purified beta2-microglobulin demonstrated the specificities of these reactions. We were able to localize beta2-microglobulin on human spermatozoa on the post-acrosomal region at a similar location to those described for HL-A antigen and for early embryonic antigen +t12, but also at the end of the intermediary piece and the beginning of the tail.

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