The expression of periostin in dental pulp cells

Archives of Oral Biology
Robert M WiesenHector F Rios

Abstract

Dental pulp repair is a common process triggered by microbial and mechanical challenges. Matricellular modulators, such as periostin, are key for extracellular matrix stability and tissue healing. In the scope of the dental pulp, periostin expression has been reported during development and active dentinogenesis. However, the specific dental pulp cell population capable of expressing periostin in response to known regulators has not been clearly defined. Among the different relevant cell populations (i.e., stem cells, fibroblasts and pre-odontoblasts) potentially responsible for periostin expression in the dental pulp, this study aimed to determine which is the primary responder to periostin regulators. Human dental pulp stem cells (DPSCs), human dental pulp fibroblasts (DPFs), and rat odontoblast-like cells (MDPC-23) were treated with different concentrations of TGF-β1 or different regimens of biomechanical stimulation to evaluate periostin expression by qRT-PCR, Western blot and ELISA. Statistical analyses were performed by Student's t-test and ANOVA with Fisher's LSD post hoc tests (p ≤ 0.05). DPSC and MDPC-23 showed a statistically significant increase in periostin mRNA expression after exposure to TGF-β1 for 48 h. TGF-β1 a...Continue Reading

References

Oct 1, 1969·Oral Surgery, Oral Medicine, and Oral Pathology·F S Sayegh
Jun 5, 1998·Clinical Oral Investigations·L StanislawskiM Goldberg
Sep 23, 2000·Archives of Oral Biology·D J Roberts-Clark, A J Smith
Feb 6, 2004·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·Michel Goldberg, Anthony J. Smith
Sep 24, 2004·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Hironobu SuzukiTakeyasu Maeda
Jan 18, 2007·Journal of Cellular Biochemistry·Russell A NorrisRoger R Markwald
Mar 21, 2007·Journal of Endodontics·Peter E MurrayKenneth M Hargreaves
Jul 22, 2008·Journal of Cell Communication and Signaling·Douglas W Hamilton
Jun 27, 2009·Biochemical and Biophysical Research Communications·V YuS O Akintoye
Jan 30, 2010·Journal of Dental Research·T M BoteroJ E Nör
Jun 29, 2010·Journal of Dentistry·Paul R CooperAnthony J Smith
Oct 14, 2010·Journal of Dental Research·W WenD W Hamilton
Dec 7, 2010·The Journal of Biological Chemistry·Dedong MaJian Q Feng
Jan 5, 2011·Frontiers in Bioscience (Elite Edition)·Michel GoldbergAdele Boskey
Jun 17, 2011·Advances in Dental Research·M Goldberg
Dec 30, 2011·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Kyoko OkaYoshihiko Sawa
Aug 31, 2012·Journal of Dental Research·M Padial-MolinaH F Rios

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Citations

Jan 16, 2016·Cellular and Molecular Life Sciences : CMLS·John BiancoAnne des Rieux
Apr 4, 2021·International Journal of Molecular Sciences·Miguel Padial-MolinaFrancisco O'Valle

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