The extent of the dorsal extra-striate deficit in amblyopia

Vision Research
Anita J SimmersR F Hess

Abstract

Previously, we have shown that humans with amblyopia exhibit deficits for global motion discrimination that cannot be simply ascribed to a reduction in visibility or contrast sensitivity. Deficits exist in the processing of global motion in the fronto-parallel plane that suggest reduced extra-striate function (i.e., MT) in amblyopia. Here, we ask whether such a deficit also exists for rotation and radial components of optic flow that are first processed at higher sites along the dorsal pathway (i.e., MSTd). We show that similar motion processing deficits occur in our amblyopic group as a whole for translation, rotation, and radial components of optic flow and that none of these can be solely accounted for by the reduced visibility of the stimuli. Furthermore, on a subject-by-subject basis there is no significant correlation between the motion deficits for radial and rotational motion and those for translation, consistent with independent deficits in dorsal pathway function up to and including MSTd.

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Citations

Jul 16, 2014·Proceedings of the National Academy of Sciences of the United States of America·Chuan HouAnthony M Norcia
Sep 10, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yasmine El-ShamaylehJ Anthony Movshon
Feb 3, 2011·Attention, Perception & Psychophysics·Zaira CattaneoTomaso Vecchi
Feb 18, 2009·The Journal of Physiology·Nigel W Daw
Oct 6, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Agnes M F Wong
Oct 6, 2012·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Benjamin Thompson
Jan 15, 2013·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Brian BrownRobert F Hess
Jan 23, 2010·The European Journal of Neuroscience·Laura K StevensDenis Schluppeck
Oct 7, 2015·Frontiers in Integrative Neuroscience·Batsheva HadadTerri L Lewis
Dec 3, 2014·Vision Research·Yi GaoRobert F Hess
Jun 7, 2015·Vision Research·Deborah GiaschiDavid Regan
Aug 5, 2010·NeuroImage·Xingfeng LiRobert F Hess
Mar 24, 2015·Vision Research·Mahesh Raj Joshi, Helle K Falkenberg
Apr 4, 2015·Journal of Ophthalmology·Hao WangZheng Qin Yin
Mar 7, 2013·Vision Research·Jesse S Husk, Robert F Hess
Mar 12, 2013·Vision Research·Jennifer Y Luu, Dennis M Levi
Jul 24, 2012·Vision Research·Craig Aaen-StockdaleRobert F Hess
Jul 4, 2012·Vision Research·Sathyasri NarasimhanDeborah E Giaschi
Feb 5, 2013·Vision Research·Zaira CattaneoClaus-Christian Carbon
Nov 14, 2006·Vision Research·Cindy S Ho, Deborah E Giaschi
Apr 20, 2007·Vision Research·Dennis M Levi
Nov 1, 2011·Vision Research·John SecenDeborah Giaschi
Apr 18, 2008·Vision Research·Benjamin ThompsonRobert F Hess
Apr 28, 2007·Vision Research·Craig Aaen-StockdaleRobert F Hess
Sep 14, 2011·Vision Research·Jake HaywardDeborah Giaschi
Jul 16, 2008·Vision Research·Craig Aaen-Stockdale, Robert F Hess
Jul 6, 2014·Frontiers in Psychology·Lisa M HammBenjamin Thompson
Jan 24, 2015·Vision Research·Brian AllenBas Rokers
Jul 25, 2013·Visual Neuroscience·Dennis M Levi
May 21, 2019·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Goro MaeharaAtsushi Miki

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