The eyelash follicle features and anomalies: A review

Journal of Optometry
Sarah Aumond, Etty Bitton

Abstract

The primary role of eyelashes is to protect and maintain the health of the lid margin. However, the mechanisms to fulfill this role are not fully understood. Unraveling these mechanisms will stand to greatly improve the efficiency of eye care professionals' interventions in anomalies of the eyelashes. The aim of this article is to provide a review on eyelashes including highlights and new avenues for research; the biology of both the lash and its follicle; the pathophysiology and management of lash anomalies by eye care professionals; and the effect of iatrogenic factors on lashes. Using the database of Ovid MEDLINE, we reviewed studies specifically directed on human/mammalian eyelashes and key articles on current trends in scalp hair methodologies that can be applicable to lash research. The eyelash morphology, pigmentation and growth rate have been documented using techniques ranging from lash imaging to follicle immunohistochemistry. Furthermore, studies have demonstrated that the lash follicle is sensitive to many factors of the external environment, a variety of systemic/topical medications and cosmetics. Recently, aerodynamic studies using a mammalian eye model confirmed that an optimal lash length was needed so that eyel...Continue Reading

Citations

May 16, 2020·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Yoshihiko EsakiNaveed K Shams
Jan 21, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Maria K WalkerStephen J Vincent
Dec 18, 2021·Journal of the European Academy of Dermatology and Venereology : JEADV·D M HutchisonN A Mesinkovska

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Methods Mentioned

BETA
electron microscopy
pharmacotherapy

Software Mentioned

Ovid

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