The fallacy of behavioral phenotyping without standardisation

Genes, Brain, and Behavior
F Josef van der Staay, T Steckler

Abstract

Behavioral phenotyping of mutant mice is a new and challenging task for the behavioral neuroscientist. Therefore, standardisation of the experimental conditions is required to permit comparisons between the results of experiments within and between laboratories. Once mutation-induced behavioral changes have been identified, phenotyping of mouse mutants should be performed along a systematic trajectory, which allows for an in-depth characterisation of the mutant under investigation.

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Related Concepts

Behavior, Animal
Psychogenetics
Mutant
Mice, Mutant Strains
Impacts, Environmental
Phenotype Determination
Mutation Abnormality
Phenotyping (Qualifier Value)

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