The Fas system may have a role in male reproduction

Fertility and Sterility
Ciler Celik-OzenciRamazan Demir

Abstract

To assess what the distributions of Fas system proteins are in normal rat testicular tissue; to assess whether there is a change in these distributions and in expression levels with experimentally-induced varicocele of 9, 11, and 13 weeks; and to assess whether there is a relationship between apoptosis and the Fas system in varicocele-induced rat testis. Comparative and controlled study. University animal care and operation unit. Wistar male rats for experimental and control groups. The control group underwent sham operation (n = 6). Rats in experimental groups underwent partial ligation of the renal vein to induce an experimental varicocele and then were killed at 9 (n = 6), 11 (n = 6), and 13 (n = 6) weeks after induction of varicocele. Tissues were fixed and processed for paraffin and Araldite embedding, and subsequently immunohistochemistry, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labeling, and transmission electron microscopy were performed. In addition, Western blotting was applied. In control testis, we detected the expression of FasL in spermatids, interestingly at the progressing stages of acrosome formation and in the heads of the spermatozoa being released to lumen. Varicocel...Continue Reading

References

Jan 1, 1979·Biulleten' eksperimental'noĭ biologii i meditsiny·S S RaĭtsinaA I Davydova
Nov 1, 1973·Journal of Reproduction and Fertility·E C Roosen-Runge
Mar 10, 1995·Science·S Nagata, P Golstein
Oct 19, 1995·Nature·D BellgrauR C Duke
May 1, 1994·International Journal of Cancer. Journal International Du Cancer·P MöllerP H Krammer
Nov 1, 1993·Urology·M A Witt, L I Lipshultz
Feb 7, 1997·Cell·S Nagata
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·J AllisonD L Vaux
Jun 1, 1997·British Journal of Urology·A AkdasK Emerk
Feb 12, 1998·Proceedings of the National Academy of Sciences of the United States of America·H AraiG J Nabel
Aug 28, 1998·Science·A Ashkenazi, V M Dixit
Apr 21, 1999·Current Opinion in Cell Biology·A Ashkenazi, V M Dixit
May 7, 1999·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·O BraendstrupL Jensen
Nov 7, 1999·World Journal of Urology·M FujisawaS Kamidono
Oct 6, 2000·Environmental Health Perspectives·J M MolineP J Landrigan
Feb 24, 2001·Human Reproduction Update·J P Jarow
Feb 24, 2001·Human Reproduction Update·T T Turner
Mar 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·A D'AlessioE Ziparo
Sep 15, 2001·Human Reproduction Update·C K NaughtonA Agarwal
Feb 28, 2002·Human Reproduction Update·J Bruce RedmonJon L Pryor
May 16, 2002·BJU International·Hiroyuki TanakaS Kamidono
Jun 18, 2003·Endocrinology·Amiya P Sinha HikimRonald S Swerdloff
Aug 1, 1962·Biological Reviews of the Cambridge Philosophical Society·E C ROOSEN-RUNGE
Nov 25, 2003·The Journal of Urology·Masato Fujisawa, Tomomoto Ishikawa
Dec 11, 2003·The Journal of Urology·Albaha BarqawiRandall B Meacham
Dec 12, 2003·Fertility and Sterility·Ramadan A SalehAnthony J Thomas
Nov 13, 2004·The Journal of Urology·Ferhat KilincHakan Ozkardes

❮ Previous
Next ❯

Citations

Jan 16, 2009·World Journal of Urology·Jane-Dar LeeShaw-Yeu Jeng
Apr 29, 2008·Fertility and Sterility·Hatem ZedanTaymour Mostafa
Mar 6, 2009·Microscopy Research and Technique·Donatella StaraceAnna Riccioli
Mar 10, 2016·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·S BayramY Topcu-Tarladacalisir
Dec 5, 2008·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·R-Marc PelletierMaría Leiza Vitale

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
A D'AlessioE Ziparo
APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica
O BraendstrupL Jensen
© 2022 Meta ULC. All rights reserved