The fate mapping of the eleventh and twelfth day mouse otocyst: an in vitro study of the sites of origin of the embryonic inner ear sensory structures

Journal of Morphology
C W LiR J Ruben

Abstract

An experiment was undertaken to determine which sensory structures of the mouse embryo inner ear developed from what portion of the mouse otocyst. Otocysts of gestation days 10, 11, 12, and 13 were divided by surgical dissection into six anatomical groups: dorsal, ventral, anterior, posterior, medial and lateral halves. They were organ cultured separately. After a period of ten days, the explanted tissues were harvested and processed histologically for microscopic analysis. The surgical control specimens fixed at the time of explantation were composed of undifferentiated ectodermal cells for tissues of gestation days 10, 11, and 12. Otocysts of gestation days 11, and 12 showed, during the course of their subsequent growth, that the three semicircular ducts and their associated cristae developed from the dorsal and lateral halves. Only the anterior and posterior canals and cristae originated from the medial portion. The posterior half gave rise to the posterior crista and the anterior half provided for the development of the anterior and lateral cristae. The cochlear duct and its sensory epithelium developed in all the anatomical groups except the dorsal half. The utricle developed in the dorsal section of the middle third of th...Continue Reading

References

Mar 1, 1978·Otolaryngology·C W Li, J McPhee
Jan 1, 1974·Brain, Behavior and Evolution·D E Hillman
Jan 1, 1973·The Annals of Otology, Rhinology, and Laryngology·T R Van de Water, R J Ruben
Sep 1, 1973·The Laryngoscope·R J Ruben
Mar 1, 1968·The Journal of Laryngology and Otology·I Friedmann
Apr 1, 1971·Acta Oto-laryngologica·T R Van de Water, R J Ruben
Jul 1, 1967·Archives of Otolaryngology·R J Ruben, R L Sidman
Mar 1, 1956·The Annals of Otology, Rhinology, and Laryngology·I FRIEDMANN
Apr 1, 1936·Proceedings of the National Academy of Sciences of the United States of America·R G Harrison

❮ Previous
Next ❯

Citations

Oct 1, 1995·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J L de la PompaR Zeller
Jan 1, 1988·Anatomy and Embryology·F Müller, R O'Rahilly
Feb 3, 1998·Hearing Research·W YangS L Mansour
Jul 1, 1997·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·K F BaraldA Poniatowski
Jan 18, 1994·Proceedings of the National Academy of Sciences of the United States of America·D J BradleyW S Young
Sep 15, 2007·Development·Ekaterina P HatchSuzanne L Mansour
Jul 23, 2003·Development·Weiming ZhengPin-Xian Xu
Jun 9, 2015·Journal of Anatomy·Martin L BaschAndrew K Groves
Jan 15, 2011·Progress in Neurobiology·Jessica M Appler, Lisa V Goodrich
Jan 17, 2015·Developmental Biology·Alexander S BrownDouglas J Epstein
Nov 1, 1984·American Journal of Otolaryngology·M Anniko, S O Wikström
Oct 23, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·G Lawoko-KeraliM C Holley
Oct 22, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Akiko T NishidaKei Tashiro
May 5, 2001·Developmental Biology·S H Kil, A Collazo
Mar 9, 2004·Mechanisms of Development·Grace Lawoko-KeraliMatthew C Holley
Sep 11, 2002·Developmental Biology·Andrea Streit
Sep 24, 2013·PloS One·Zoe F MannMatthew W Kelley
Sep 12, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·H O SedanoA B Moleri
Jul 25, 2000·Mechanisms of Development·M Hidalgo-SánchezI S Alvarez
Nov 1, 1984·The Annals of Otology, Rhinology, and Laryngology·T R Van de Water, R J Ruben
May 1, 1981·The Annals of Otology, Rhinology, and Laryngology·G L Davis, M M Hawrisiak
Jul 1, 1980·The Annals of Otology, Rhinology, and Laryngology·R J Ruben, I Rapin
Jun 1, 1990·The Annals of Otology, Rhinology, and Laryngology·J J RepresaE Barbosa
Dec 23, 2003·The Journal of Comparative Neurology·Kim CrynsGuy van Camp
Jan 28, 2004·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Lisa M Gerlach-BankKate F Barald
Apr 30, 2003·The Journal of Comparative Neurology·Jennifer S StoneStanislav Tomarev
Oct 17, 2002·Journal of Neurobiology·Sung-Hee Kil, Andres Collazo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Lymphoproliferative Syndrome

Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis. Discover the latest research on ALPS here.