The feasibility and acceptability of a novel anxiety in bipolar disorder intervention compared to treatment as usual: A randomized controlled trial.

Depression and Anxiety
Steven JonesLisa Riste

Abstract

Comorbid anxiety is common in bipolar disorder (BD) and associated with worse clinical outcomes including increased suicidality. Despite effective psychological treatments for anxiety, research into treating anxiety in BD is underdeveloped. This paper describes a novel psychological intervention to address anxiety in context of bipolar disorder (AIBD). Adults with BD and clinically significant anxiety symptoms were randomized to AIBD plus treatment as usual (TAU) or TAU alone. AIBD offered 10 sessions of psychological therapy using a formulation-based approach. Feasibility and acceptability were evaluated through recruitment, retention, therapy attendance, alliance, fidelity, and qualitative feedback. Clinical outcomes were assessed at baseline, 16, 48, and 80 weeks: interim assessments of relapse at 32 and 64 weeks. Seventy-two participants were recruited with 88% retention to 16 weeks and 74% to 80 weeks (similar between arms). Therapy participants attended <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow><mml:mover><mml:mi>x</mml:mi> <mml:mo>¯</mml:mo></mml:mover> <mml:mspace/></mml:mrow> </mml:math> 7.7 (SD 2.8) sessions. Therapeutic alliance and therapy fidelity were acceptable. Qualitative interviews in...Continue Reading

References

Jun 1, 1978·Neuropharmacology·P BechT G Bolwig
Jul 29, 1989·BMJ : British Medical Journal·C R Brewin, C Bradley
Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Jan 29, 2005·The American Journal of Psychiatry·Dominic H LamPak Sham
Apr 4, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Jan ScottHazel Hayhurst
Jul 4, 2006·The British Journal of Psychiatry : the Journal of Mental Science·M W OttoUNKNOWN STEP-BD Investigators
Dec 13, 2006·Bipolar Disorders·Roger S McIntyreSidney H Kennedy
Feb 27, 2007·Journal of Anxiety Disorders·Roger CovinDavid J A Dozois
May 9, 2007·Archives of General Psychiatry·Kathleen R MerikangasRonald C Kessler
Aug 14, 2008·The British Journal of Psychiatry : the Journal of Mental Science·Andrew J A Keen, Mark H Freeston
Mar 26, 2010·BMC Medicine·Kenneth F SchulzUNKNOWN CONSORT Group
Nov 3, 2010·Bipolar Disorders·Erin E MichalakUNKNOWN Collaborative RESearch Team to Study Psychosocial Issues in Bipolar Disorder (CREST.BD)
Nov 26, 2010·Journal of Affective Disorders·Martin D ProvencherEmmanuelle Thienot
Apr 27, 2012·Journal of Psychiatric Research·Regina SalaCarlos Blanco
May 4, 2012·Depression and Anxiety·David Goldberg, Jan Fawcett
Jun 14, 2013·Journal of Affective Disorders·Mark ZimmermanKristy Dalrymple
Oct 1, 2013·The American Journal of Psychiatry·Thilo DeckersbachAndrew Nierenberg
Sep 13, 2014·The British Journal of Psychiatry : the Journal of Mental Science·Steven H JonesAnthony P Morrison
Dec 3, 2014·Clinical Psychology Review·Hannah J StratfordEmily A Holmes
Oct 26, 2016·BMJ : British Medical Journal·Sandra M EldridgeUNKNOWN PAFS consensus group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.