The feline thyroid gland: a model for endocrine disruption by polybrominated diphenyl ethers (PBDEs)?

Journal of Toxicology and Environmental Health. Part a
Donna A MenschingVal R Beasley

Abstract

The role of polybrominated diphenyl ethers (PBDE) was investigated in the occurrence of feline hyperthyroidism (FH) by evaluating 15 PBDE congeners in serum from 62 client-owned (21 euthyroid, 41 hyperthyroid) and 10 feral cats. Total serum PBDE concentrations in euthyroid cats were not significantly different from those of hyperthyroid cats. Total serum PBDE in feral cats were significantly lower than in either of the groups of client-owned cats. Total serum PBDE did not correlate with serum total T4 concentration. Ten samples of commercial canned cat food and 19 dust samples from homes of client-owned cats were analyzed. Total PBDE in canned cat food ranged from 0.42 to 3.1 ng/g, and total PBDE in dust from 510 to 95,000 ng/g. Total PBDE in dust from homes of euthyroid cats ranged from 510 to 4900 ng/g. In dust from homes of hyperthyroid cats, total PBDE concentrations were significantly higher, ranging from 1100 to 95,000 ng/g. Dust PBDE and serum total T4 concentration were also significantly correlated. Estimates of PBDE exposures calculated from canned cat food and dust data suggest that domestic cats are primarily exposed through ingestion of household dust. These findings indicate further study of the role of PBDE is ne...Continue Reading

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Citations

Jul 17, 2013·Environmental Science & Technology·Haijie CaoSide Yao
Dec 25, 2015·Environmental Science & Technology·Weihong GuoJune-Soo Park
Sep 19, 2015·Reproduction in Domestic Animals = Zuchthygiene·Ulf Magnusson, Sara Persson
Mar 26, 2015·Environmental Science & Technology·Jessica NorrgranÅke Bergman
May 5, 2016·Journal of Feline Medicine and Surgery·Hazel C CarneyA Renee Rucinsky
Nov 5, 2014·Journal of Feline Medicine and Surgery·Ingrid van HoekVincent Biourge
Feb 17, 2015·Journal of the South African Veterinary Association·Joanne L McLeanJohan P Schoeman
Oct 23, 2012·Journal of Feline Medicine and Surgery·Mark Peterson
May 19, 2017·Epidemiology·Marc G Weisskopf, Thomas F Webster
May 22, 2020·The Journal of Veterinary Medical Science·Kraisiri KhidkhanMayumi Ishizuka
Oct 5, 2019·Acta Veterinaria Scandinavica·Bernt JonesJana Weiss
Jun 17, 2020·Journal of Feline Medicine and Surgery·Simona KovaříkováJarmila Konvalinová
Nov 8, 2014·The Veterinary Record·Hans S Kooistra
Nov 2, 2014·The Veterinary Record·Keshuan ChowMax Zuber
Jul 11, 2019·Environmental Science & Technology·Carolyn M PoutasseKim A Anderson

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