PMID: 9537059Jan 1, 1980Paper

The fetus as an allograft: a longitudinal study of normal human pregnancies studied with mixed lymphocyte cultures between mother-father and mother-child

Scandinavian Journal of Immunology
S A Birkeland, K Kristoffersen

Abstract

A longitudinal investigation of the mixed lymphocyte culture (MLC) response during pregnancy between mother and father, between mother and child, and between the mother and an indifferent lymphocyte pool has been carried out, using starting values before pregnancy and a cryobiological freezing system that allows in vitro playback of the immunological course of pregnancy. Lymphocyte and serum samples from twenty-two pregnant women taken before and during pregnancy, at delivery, and after delivery were used. The study shows that the mother reacts during the course of pregnancy with an increasing MLC response to the father, which is replaced at delivery by a decrease in response and a subsequent increase after delivery. It is also shown that the mother reacts to the child in a similar manner at about half the level of reaction to the father. The mother also reacts similarly to a pool of indifferent lymphocytes. The MLC reactions mentioned are affected by both non-pregnant and pregnant serum, leading to a moderation of the MLC reaction in relation to that carried out in neutral AB serum. In addition, there seems to be cooperation between cellular and humoral factors, since the MLC reaction to the child carried out in relevant autol...Continue Reading

References

Jan 1, 1976·Scandinavian Journal of Immunology·R A Murgita
Dec 15, 1973·FEBS Letters·B Von SchoultzA Tärnvik
Jul 15, 1974·American Journal of Obstetrics and Gynecology·B von Schoultz
Jul 1, 1973·The Journal of Obstetrics and Gynaecology of the British Commonwealth·E JonesJ M Gaugas
Jan 1, 1980·Scandinavian Journal of Immunology·S A Birkeland, K Kristoffersen

❮ Previous
Next ❯

Citations

Jan 31, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·B Daunter
Jan 1, 1984·Journal of Reproductive Immunology·J Stankova, M Rola-Pleszczynski
Feb 1, 1985·Journal of Reproductive Immunology·I L Sargent, C W Redman
Jun 1, 2006·Current Opinion in Obstetrics & Gynecology·Ole B Christiansen
Jan 1, 1996·American Journal of Reproductive Immunology : AJRI·L KomlosI Halbrecht
Oct 1, 1989·American Journal of Reproductive Immunology : AJRI·L KomlosI Halbrecht
Sep 1, 1983·American Journal of Reproductive Immunology : AJRI·N S Kosower, R Shomrat
Mar 1, 1984·American Journal of Reproductive Immunology : AJRI·S A Birkeland, K Kristoffersen
Apr 12, 2005·Fertility and Sterility·Ole B ChristiansenKatrin van der Ven
Oct 1, 1980·Immunology Today·P Toivanen, C Granberg
May 1, 1982·Infection and Immunity·A A van ZonA A Koekkoek

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.