PMID: 9529610Apr 8, 1998Paper
The fight of viruses against apoptosis
Current Opinion in Genetics & Development
J TschoppE Meinl
Abstract
The induction of apoptosis of virus-infected cells is an important host defense mechanism against invading pathogens. Some viruses express anti-apoptotic proteins that efficiently block apoptosis induced by death receptors or in response to stress signaled through mitochondria. Viral interference with host cell apoptosis leads to enhanced viral replication and may promote cancer.
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