The first case of severe novel H1N1 influenza successfully rescued by extracorporeal membrane oxygenation in Taiwan

Journal of the Formosan Medical Association = Taiwan Yi Zhi
Tsui-Mai KaoShan-Chwen Chang

Abstract

During the novel influenza A (H1N1) pandemic, some patients developed acute respiratory distress syndrome or severe cardiopulmonary failure despite the use of conventional management. Extracorporeal membrane oxygenation (ECMO) support may successfully rescue these severely ill patients. Here, we report the first case of severe novel H1N1 infection with multiorgan failure that was successfully treated with antiviral therapy and ECMO in Taiwan. A 32-year-old man had acute onset of fever, dry cough, rhinorrhea, and sore throat 2 days after returning from Dongguan, China. He attended Hospital A and chest radiography revealed bilateral lung consolidation. Rapid influenza antigen testing was negative. He was intubated 2 days later due to hypoxic respiratory failure and persistent shock refractory to conventional management. Because of compromised cardiopulmonary function, venoarterial ECMO support was started 4 days after the onset of symptoms and he was transferred to Hospital B on July 25, 2009. As history taking found clustering of influenza-like illness, oseltamivir was given immediately under the impression of severe influenza illness. Real-time reverse transcriptase-polymerase chain reaction of respiratory sample for novel H1N1...Continue Reading

References

Apr 28, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Wen-Je KoPi-Ru Tsai
Jan 18, 2008·The New England Journal of Medicine·UNKNOWN Writing Committee of the Second World Health Organization Consultation on Clinical Aspects of Human Infection with Avian InfTimothy M Uyeki
Jul 17, 2008·Chest·Douglas J E SchuererCraig M Coopersmith
Mar 14, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Scott A HarperUNKNOWN Expert Panel of the Infectious Diseases Society of America
Mar 28, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Timothy M UyekiArnold S Monto
Sep 4, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Shawn VasooKamaljit Singh

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Citations

May 7, 2011·Surgical Infections·Kristen C Sihler, Pauline K Park
Jul 12, 2011·Critical Care Clinics·Pauline K ParkRobert H Bartlett
Jun 17, 2010·American Journal of Clinical Pathology·Paul W HarmsJeffrey M Jentzen
Nov 27, 2014·Human Vaccines & Immunotherapeutics·Yuichiro IdeYoshio Hirota

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