The first description of rheumatoid arthritis. Unabridged text of the doctoral dissertation presented in 1800

Joint, Bone, Spine : Revue Du Rhumatisme
A J Landré-Beauvais

Abstract

This unabridged version of the dissertation presented in 1800 by Augustin Jacob Landré-Beauvais for his medical doctorate describes a disease different in many ways from the condition known since Hippocrates as gout. The patients were nine long-term residents of the Salpêtrière hospice in Paris. After reviewing the main features of ordinary or regular gout, Landré-Beauvais points out that the disease he calls "asthenic gout" exhibits several distinctive features, including predominance in women, a chronic course, involvement of many joints from the onset, and a decline in general health. Despite the tentative tone of his title ("Should one recognize...), he clearly is convinced that he is describing an as yet unreported entity, as indicated by the last sentence of his dissertation: "...we must recognize the existence of a new form of gout under the designation primary asthenic gout" And although he stops short of emancipation from the term "gout", which had been used for centuries to designate specific joint manifestations, he makes several keenly discerning observations -- particularly regarding the influence of psychological factors, the need for gentle treatments, and the inappropriateness of bloodletting - thus breaking fre...Continue Reading

Citations

Oct 24, 2014·Radiology·Mingqian Huang, Mark E Schweitzer
Feb 24, 2016·Mediators of Inflammation·Reka KugyelkaFerenc Boldizsar
Nov 16, 2004·The Spine Journal : Official Journal of the North American Spine Society·Francis H ShenHoward S An
Nov 20, 2009·Scandinavian Journal of Rheumatology·S E Hansen
Dec 24, 2010·Hand Clinics·Pouya EntezamiKevin C Chung
Sep 11, 2016·Trends in Cardiovascular Medicine·Katherine P Liao
Sep 1, 2007·Scandinavian Journal of Rheumatology·S E Hansen, A Wallenquist
Jul 12, 2017·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Aitor CazonR Ian Campbell
Nov 30, 2006·The American Journal of Sports Medicine·Michael BahkEdward G McFarland
May 31, 2017·Seminars in Immunopathology·Sebastien Viatte, Anne Barton
Aug 29, 2019·Journal of Clinical Medicine·Eduardo Gómez-BañuelosFelipe Andrade
Sep 28, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Roger NewMichael Burnet
Oct 13, 2020·Critical Reviews in Biotechnology·Muhammad Safwan AkramAli K Yetisen
Apr 15, 2021·Nature Reviews. Rheumatology·Olufemi AdelowoSamy Slimani
Dec 10, 2019·Joint, Bone, Spine : Revue Du Rhumatisme·Marie-Christophe BoissierNatacha Bessis
Sep 9, 2021·Clinical Reviews in Allergy & Immunology·Maria V SokolovaUlrike Steffen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.