The First Live Birth in Lithuania After Application of Preimplantation Genetic Testing.

Acta Medica Lituanica
Živilė GudlevičienėDiana Ramašauskaitė

Abstract

Preimplantation genetic testing (PGT) is a genetic testing procedure that is performed before the implantation of embryos for the identification of genetic abnormalities. It is commonly performed when one or both expecting parents have such abnormalities and are at a high risk of passing them to their offspring. The aim of this case report is to describe the first successful IVF/ICSI/PGT procedure in Lithuania. A 27-year-old woman and a 31-year-old man, a married couple, were referred to VUHSK Santaros Fertility Center after trying to conceive for 4 years. In a previous relationship, the woman got pregnant spontaneously and decided to terminate the pregnancy. The husband does not have any children. During the medical examination, the transvaginal ultrasound revealed a low antral follicle count and low anti-Müllerian hormone level for the woman. Semen analysis for the male patient showed severe oligoastenospermia, which confirmed the previous abnormal spermogram results. Chromosome analysis revealed normal karyotype for the woman (46,XX) and Robertsonian translocation for the husband (45,XY,der(13;14)(q10;q10)). After the interdisciplinary medical team counselling, an ICSI with PGT-SR was suggested for the couple. The woman unde...Continue Reading

References

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Feb 23, 2019·Journal of Human Reproductive Sciences·Firuza Rajesh ParikhProchi Fali Madon
Jun 6, 2020·Human Reproduction Open·UNKNOWN ESHRE PGT-SR/PGT-A Working GroupMartine De Rycke
Jun 6, 2020·Human Reproduction Open·UNKNOWN ESHRE PGT-M Working GroupMartine De Rycke
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