The follow-up study of skin reactivity to recall antigens and E- and EAC-RFC profiles in blood in asbestos workers

Immunobiology
A LangeD Garncarek

Abstract

We have determined cutaneous DTH reactions to SK-SD and PPD and peripheral blood lymphocyte profiles in a group of asbestos workers in two consecutive surveys. It was found that asbestosis and, to a lesser extent, the presence of ANA are significantly correlated with the lack of response to the above antigens. 83% of asbestos workers when tested at a 4 year interval fell into the same two categories of responsiveness (lack of response or response at least to one antigen). The asbestosis cases had lower total lymphocyte count as well as proportions and absolute number of E-RFC as compared to asbestos workers without asbestosis and/or ANA. Furthermore, the latter group showed the lower percentages and absolute number of E-RFC than the matched controls. The presence of ANA is also correlated with lower proportions of E-RFC. However, this is related at least in part to asbestosis.

References

Feb 1, 1977·Thorax·H L RobertsD A Price Evans
Jan 1, 1975·The Journal of Experimental Medicine·P H Lagrange, G B Mackaness
Apr 1, 1974·European Journal of Immunology·G Brown, M F Greaves
Oct 18, 1974·Nature·K SchumacherU Wehmer
Jan 1, 1974·Scandinavian Journal of Immunology·G Brown, M F Greaves
Jan 31, 1974·Internationales Archiv Für Arbeitsmedizin·A LangeJ Szymańska
Aug 29, 1970·British Medical Journal·M Turner-Warwick, W R Parkes
Dec 31, 1965·Annals of the New York Academy of Sciences·B PernisI J Selikoff

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Citations

Apr 1, 1983·Environmental Research·B E BozelkaJ E Salvaggio
Apr 16, 1998·Environmental Health Perspectives·G J RosenthalP Simeonova
Jan 1, 1984·Toxicology and Applied Pharmacology·G A BoormanH L Hong
Jun 18, 1999·Reviews on Environmental Health·G J RosenthalE Corsini

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