PMID: 494Oct 1, 1975

The formation of synapses in amphibian striated muscle during development

The Journal of Physiology
M R Bennett, A G Pettigrew

Abstract

1. A study has been made of the formation of synapses in developing reinnervated and cross-reinnervated amphibian twitch muscles which receive either a focal (iliofibularis) or a distributed (sartorius) innervation from 'en plaque' nerve terminals using histological, ultrastructural and electrophysiological techniques. 2. During the development of the tadpole through metamorphosis to the adult frog, the sartorius myofibres increased in length at about twice the rate of the iliofibularis myofibres, due to a fast rate of growth at their insertions on to the pelvic tendon. 3. The short iliofibularis and sartorius myofibres of young tadpoles (800 mum long) possessed only a single synapse and the iliofibularis myofibres did not receive any further innervation during development. However the sartorius myofibres received further transient innervation on the new muscle laid down during development at the fast growing pelvic insertion, until the distance between the original synapse formed on the myofibres and the synapse at the pelvic end of the muscle was about 12 mm. 4. During development synapses possessed either skewed, multimodal, or unimodal m.e.p.p. amplitude-frequency distributions; the intervals between m.e.p.p.s. were not dis...Continue Reading

Citations

Jan 1, 1983·Biological cybernetics·J L GouzéJ P Changeux
Jul 1, 1995·Progress in Neurobiology·M R Bennett
Feb 1, 1985·Journal of Neurocytology·A A Herrera, D R Scott
Dec 1, 1976·Journal of Neurocytology·S Rotshenker, U J McMahan
Jun 1, 1980·Journal of Neurocytology·M S Letinsky, K Morrison-Graham
Dec 1, 1985·Journal of Neurocytology·M R BennettNickolas Lavidis
Aug 1, 1981·Journal of Neurocytology·M B Rheuben, A E Kammer
Dec 1, 1996·Journal of Neurocytology·M R Bennett
Jan 1, 1983·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·J M ThompsonM Nirenberg
May 1, 1983·Developmental Biology·K Lynch, C P Ko
Mar 25, 1985·Brain Research·B Nudell, A D Grinnell
Jan 1, 1990·Annals of the New York Academy of Sciences·J A Brock, T C Cunnane
Apr 25, 1977·Pflügers Archiv : European journal of physiology·F Vyskocil, L G Magazanik
Sep 1, 1984·Pflügers Archiv : European journal of physiology·J LehouelleurH Schmidt
May 1, 1985·Journal of Neurobiology·L W Klaassen, A E Kammer
Sep 15, 1980·The Journal of Comparative Neurology·S Rotshenker, F Reichert
Nov 1, 1992·The Journal of Comparative Neurology·F F Omerza, K E Alley
Jan 1, 1990·Journal of Neurobiology·A A Herrera, M J Werle
Apr 23, 1990·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·M R Bennett, J Robinson
Jun 24, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Dengyun Ge, Nickolas Lavidis
Jan 1, 1979·The American Journal of Physiology·A R Luff, U Proske

Related Concepts

Amphibians
Metazoa
Salientia
Bufo marinus
Electrophysiology (Science)
Tadpole
Biological Metamorphosis
Muscle Denervation Procedure
Muscle
Myofilaments

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