The frequency and clinical significance of specific IgE to both wasp (Vespula) and honey-bee (Apis) venoms in the same patient

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology
W EgnerP W Ewan

Abstract

Changeover from Phadebas RAST to Pharmacia AutoCAP increased double-positivity to both honey-bee and common wasp (vespula) venom in our patients. We examined the frequency of IgE double-positivity, its clinical relevance and utility in investigating potentially allergic patients. One hundred and eighty-two patients with hymenoptera allergy were tested using RAST (n = 51) and AutoCAP (n = 131) assays over 4 years. Patients had a history of reactions to vespulae (22), honey-bee (10) and unidentified hymenoptera (vespinae) (7). After changing from RAST to AutoCAP double-positivity increased from 10 (5/ 51) to 30% (39/131) (P < 0.01). RAST and CAP assays gave similar median class results (vespula = 3, honey-bee = 2). Thirty-six CAP patients had systemic reactions of Mueller grade II and above. In vespula-allergic double-positive subjects, high CAP classes (> or = class 3) to honey-bee were common (30%). In 25% the CAP classes were equal. In honey-bee-allergic subjects, all vespula venom CAP IgE was low titre (class 1 or 2) and 20% were equal for both venoms. In 43% of vespinae-allergic patients the CAP class was equal to both (class 2 and 3). In contrast, intradermal skin test double-positivity was uncommon. Double-negative skin te...Continue Reading

References

Sep 1, 1992·The Journal of Allergy and Clinical Immunology·D CharpinD Vervloet
Feb 1, 1992·Mayo Clinic Proceedings·J T Li, J W Yunginger
Mar 1, 1991·The Journal of Allergy and Clinical Immunology·L HaugaardR Dahl
Jan 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A LeimgruberA Pécoud
Jan 1, 1990·Allergy Proceedings : the Official Journal of Regional and State Allergy Societies·D CharpinJ Charpin
Jan 1, 1989·International Archives of Allergy and Applied Immunology·R E Reisman, J M DeMasi
Mar 1, 1989·Allergy Proceedings : the Official Journal of Regional and State Allergy Societies·G A Settipane, G K Boyd
Jul 14, 1989·JAMA : the Journal of the American Medical Association·D B GoldenL M Lichtenstein
Aug 1, 1989·The Journal of Allergy and Clinical Immunology·D B GoldenL M Lichtenstein
Nov 1, 1988·The Journal of Allergy and Clinical Immunology·D R HoffmanC T Stafford
Sep 1, 1987·Clinical Allergy·Y Green-Graif, P W Ewan
Nov 1, 1987·The Journal of Allergy and Clinical Immunology·M N Savliwala, R E Reisman
Jan 1, 1987·International Archives of Allergy and Applied Immunology·R E ReismanM I Lazell
Mar 1, 1985·Journal of the Royal Society of Medicine·P W Ewan
Feb 1, 1984·The Journal of Allergy and Clinical Immunology·R E ReismanM I Lazell
Nov 1, 1981·The Journal of Allergy and Clinical Immunology·R C AalberseJ G Clemens
Nov 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D CharpinD Vervloet
Oct 1, 1994·The Journal of Allergy and Clinical Immunology·R E Reisman
Mar 1, 1994·Allergy Proceedings : the Official Journal of Regional and State Allergy Societies·S D MillerG K Boyd
Apr 1, 1994·The Journal of Allergy and Clinical Immunology·J H DayA C Welsh
Aug 1, 1993·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P W EwanP J Lachmann

❮ Previous
Next ❯

Citations

Feb 13, 2008·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·W Hemmer
Jun 15, 2006·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Rj Warrington
Apr 16, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·U R Müller
Dec 21, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·I Annila
May 1, 2005·Expert Review of Clinical Immunology·Didier G EboWim J Stevens
Feb 5, 2014·Expert Review of Clinical Immunology·Didier G EboVito Sabato
Oct 15, 2011·Cutaneous and Ocular Toxicology·Mark M Neis, Hans F Merk
Feb 15, 2015·Clinica Chimica Acta; International Journal of Clinical Chemistry·A L Van GasseD G Ebo
Dec 1, 2015·European Journal of Immunology·Sai Harsha Krovi, Laurent Gapin
Mar 10, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·W HemmerR Jarisch
Nov 6, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A Gonzalez-QuintelaC Vidal
Aug 30, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L DiwakarM T Krishna
Nov 7, 2006·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·V MahlerT Fuchs
Aug 19, 2011·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M T KrishnaUNKNOWN British Society for Allergy and Clinical Immunology
Jun 16, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M MertensR Brehler
Jan 22, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·D G EboL S De Clerck
Mar 7, 2014·Toxicon : Official Journal of the International Society on Toxinology·Débora Laís Justo JacominiMárcia Regina Brochetto Braga
Jul 4, 2015·Current Allergy and Asthma Reports·Markus Ollert, Simon Blank
Nov 26, 2013·Allergology International : Official Journal of the Japanese Society of Allergology·Yumeko HayashiYoshiki Ishii
Sep 6, 2012·Allergy, Asthma & Immunology Research·Yoo Seob ShinHae-Sim Park
Nov 17, 2009·The Journal of Allergy and Clinical Immunology·Chunsheng JinWolfgang Hemmer
Jan 15, 2015·The Journal of Experimental Medicine·Elvire A BourgeoisGraham Ogg
Sep 14, 2016·Forensic Science International : Synergy·Lara TranCristian Palmiere
Sep 6, 2013·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Johanna StoevesandtAxel Trautmann
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Kalliopi Kontou-Fili
May 16, 2017·Current Allergy and Asthma Reports·D Tomsitz, K Brockow
Jul 20, 2002·Current Opinion in Allergy and Clinical Immunology·Robert G Hamilton
Jan 1, 2014·Allergology International : Official Journal of the Japanese Society of Allergology·Yumeko HayashihYoshiki Ishii

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

© 2022 Meta ULC. All rights reserved