PMID: 1206629Nov 1, 1975Paper

The frequency of aneuploidy in the secondary spermatocytes of normal and Robertsonian translocation-carrying rams

Journal of Reproduction and Fertility
H M Chapman, A N Bruère

Abstract

A detailed analysis was made of the chromosomes in 1008 M II figures from three different types of heterozygous Robertsonian translocation-carrying rams (53,xy,t1; 53,xy,t3) and 225 M II figures from homozygous Robertsonian translocation-carrying rams (52,xy,t1t1; 52,xy,t3t3) and rams of normal karotype (54,xy). No hypermodal cells were recorded in either the normal or the homozygous rams, but from 4-5% to 9-2% of M II cells from the heterozygous rams were hypermodal. The heterozygous rams also produced a significantly higher level of hypomodal cells suggesting that, in addition to non-disjunction, lagging at anaphase I may have occurred. There were also distinct differences in M II aneuploid spermatocyte frequency between heterozygous versus normal and homozygous rams. Fewer balanced translocation X-carrying M II cells were recorded than expected in three of the four 53,xy,t2 rams. This coincides with mating data which suggest that 26,x,t2 gametes may occur less frequently than expected. Since ewes of normal karotype mated to 53,xy,t rams conceive to first service at a rate equal to or better than normal mating groups, and because no blastocysts with unbalanced karotypes associated with the t1 translocation have been recorded,...Continue Reading

Citations

Nov 29, 1976·Chromosoma·E CapannaM V Civitelli
Jan 1, 1994·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·S C KingswoodI F Greenbaum
Sep 1, 1981·Journal of Reproductive Immunology·R P EricksonM Butley
Dec 1, 1975·New Zealand Veterinary Journal·A N Bruere
Jul 1, 1977·Journal of Dairy Science·W F Blazak, F E Eldridge
Mar 1, 1977·Canadian Journal of Genetics and Cytology. Journal Canadien De Génétique Et De Cytologie·H M Chapman, A N Bruère

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