The Frontal Control of Stopping

Cerebral Cortex
Ashwani JhaVladimir Litvak

Abstract

Stopping is a critical aspect of brain function. Like other voluntary actions, it is defined by its context as much as by its execution. Its neural substrate must therefore reflect both. Here, we distinguish those elements of the underlying brain circuit that preferentially reflect contextual aspects of stopping from those related to its execution. Contextual complexity of stopping was modulated using a novel "Stop/Change-signal" task, which also allowed us to parameterize the duration of the stopping process. Human magnetoencephalographic activity and behavioral responses were simultaneously recorded. Whereas theta/alpha frequency activity in the right inferior frontal gyrus was most closely associated with the duration of the stopping process, earlier gamma frequency activity in the pre-supplementary motor area was unique in showing contextual modulation. These results differentiate the roles of 2 key frontal regions involved in stopping, a crucial aspect of behavioral control.

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Citations

Jun 28, 2015·Neuroscience and Biobehavioral Reviews·J Leon Kenemans
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Aug 27, 2021·Human Brain Mapping·Jessica M CassidySteven C Cramer
Dec 15, 2021·Social Cognitive and Affective Neuroscience·Bochao ChengJiaojian Wang

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Methods Mentioned

BETA
SMA

Software Mentioned

Psignifit
Matlab scripts

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