The FtsK family of DNA translocases finds the ends of circles

Journal of Molecular Microbiology and Biotechnology
Estelle CrozatFrançois Cornet

Abstract

A global view of bacterial chromosome choreography during the cell cycle is emerging, highlighting as a next challenge the description of the molecular mechanisms and factors involved. Here, we review one such factor, the FtsK family of DNA translocases. FtsK is a powerful and fast translocase that reads chromosome polarity. It couples segregation of the chromosome with cell division and controls the last steps of segregation in time and space. The second model protein of the family SpoIIIE acts in the transfer of the Bacillus subtilis chromosome during sporulation. This review focuses on the molecular mechanisms used by FtsK and SpoIIIE to segregate chromosomes with emphasis on the latest advances and open questions.

Citations

Nov 26, 2016·Molecular Microbiology·Helena Veiga, Mariana G Pinho
Mar 10, 2018·PLoS Genetics·Anurag Kumar SinhaBénédicte Michel
May 1, 2020·Frontiers in Microbiology·Monika Pióro, Dagmara Jakimowicz
Feb 25, 2017·PloS One·Luz Adriana Vega-CabreraLiliana Pardo-López
Jun 19, 2016·Proceedings of the National Academy of Sciences of the United States of America·Florian FournesPhilippe Rousseau
Jan 21, 2021·Molecular Cell·Xheni KarabojaXindan Wang
Sep 30, 2020·FEMS Microbiology Reviews·Alix MeunierManuel Campos

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