PMID: 5971009Sep 1, 1966Paper

The function of the golgi complex in transitional epithelium. Synthesis of the thick cell membrane

The Journal of Cell Biology
R M Hicks

Abstract

The superficial squamous cells of rat transitional epithelium are limited, on their luminal face, by an asymmetrically thickened membrane. Patches of similar thick membrane are found in the walls of the Golgi cisternae and it is suggested that the Golgi system is the site of assembly of the thick plasma membrane. This implies membrane flow from the Golgi apparatus to the cell surface, and there is indirect evidence that the membrane is transported in the form of fusiform vacuoles, derived from the Golgi cisternae, which fuse with, and become part of, the free cell membrane. Uptake of injected Imferon shows that similar, large, thick-walled vacuoles may be formed by invagination of the free cell surface. Some of these vacuoles are subsequently transformed into multivesicular bodies and autophagic vacuoles. The formation of other large heterogeneous bodies is described, and some of these are shown to have acid phosphatase activity.

References

Jul 1, 1965·The Journal of Cell Biology·R M Hicks
Feb 1, 1961·The Journal of Biophysical and Biochemical Cytology·J H LUFT
Apr 1, 1963·The Journal of Cell Biology·H H MOLLENHAUER, W G WHALEY
Feb 1, 1964·The Journal of Cell Biology·T F ROTH, K R PORTER
Sep 17, 1964·Zeitschrift für Zellforschung und mikroskopische Anatomie·E W DANIELS
Feb 1, 1965·The Journal of Cell Biology·N M KANCZAKW B ELLIOTT
Jul 1, 1965·The American Journal of Anatomy·D S FRIEND, M J MURRAY

❮ Previous
Next ❯

Citations

Oct 16, 2002·Cell Motility and the Cytoskeleton·Peter Veranic, Kristijan Jezernik
Jun 16, 2001·Cell Biology International·R RomihK Jezernik
Jan 1, 1982·Anatomy and Embryology·K Tiedemann
Jan 1, 1972·Zeitschrift für Zellforschung und mikroskopische Anatomie·G R Campbell, Y Uehara
May 3, 1979·Anatomy and Embryology·K Tiedemann
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·B Monis, D Zambrano
Jan 1, 1968·Zeitschrift für Zellforschung und mikroskopische Anatomie·B Monis, D Zambrano
Jan 1, 1971·Zeitschrift für Zellforschung und mikroskopische Anatomie·W W FrankeS Krien
Jan 1, 1969·Zeitschrift Für Anatomie Und Entwicklungsgeschichte·M Sano, F Sasaki
Jan 1, 1984·The Journal of Membrane Biology·S A LewisJ M Diamond
Jan 1, 1980·The Journal of Membrane Biology·G GronowiczE Holtzman
Sep 7, 2007·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Milan Chromek, Annelie Brauner
Apr 17, 2009·Cell and Tissue Research·Samo HudoklinRok Romih
Jun 4, 2010·Protoplasma·Mateja Erdani KreftRok Romih
Jan 1, 1973·International Journal for Parasitology·D J Hockley, D J McLaren
Sep 1, 1995·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·D B ClaysonS M Cohen
Oct 10, 2008·Proceedings of the National Academy of Sciences of the United States of America·Puneet KhandelwalGerard Apodaca
Sep 1, 1968·The Journal of Cell Biology·J G HirschZ A Cohn
Oct 1, 1969·The Journal of Cell Biology·H Falk
Feb 1, 1970·The Journal of Cell Biology·A R Hand
Sep 1, 1970·The Journal of Cell Biology·G E Wise, C J Flickinger
Apr 1, 1974·The Journal of Cell Biology·J VergaraH Elrod
Aug 1, 1980·The Journal of Cell Biology·J D Robertson, J Vergara
Mar 22, 2002·Molecular Biology of the Cell·Steven T TruschelGerard Apodaca
May 1, 1975·Biological Reviews of the Cambridge Philosophical Society·R M Hicks
Jul 10, 2009·American Journal of Physiology. Renal Physiology·Puneet KhandelwalGerard Apodaca
Sep 3, 2011·PloS One·Samo HudoklinRok Romih
Mar 1, 1974·Kidney International·F J Silverblatt

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Landau-Kleffner Syndrome

Landau Kleffner syndrome (LKS), also called infantile acquired aphasia, acquired epileptic aphasia, or aphasia with convulsive disorder, is a rare childhood neurological syndrome characterized by the sudden or gradual development of aphasia (the inability to understand or express language) and an abnormal electroencephalogram. Discover the latest research on LKS here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.