The function of the oxylipin 12-oxophytodienoic acid in cell signaling, stress acclimation, and development

Journal of Experimental Botany
Daniel MaynardKarl-Josef Dietz

Abstract

Forty years ago, 12-oxophytodienoic acid (12-OPDA) was reported as a prostaglandin (PG)-like metabolite of linolenic acid found in extracts of flaxseed. Since then, numerous studies have determined the role of 12-OPDA in regulating plant immunity, seed dormancy, and germination. This review summarizes our current knowledge of the regulation of 12-OPDA synthesis in the chloroplast and 12-OPDA-dependent signaling in gene expression and targeting protein functions. We describe the properties of OPDA that are linked to the activities of PGs, which are derived from arachidonic acid and act as tissue hormones in animals, including humans. The similarity of OPDA with bioactive PGs is particularly evident for the most-studied cyclopentenone, PG 15-dPGJ2. In addition to chemical approaches towards 12-OPDA synthesis, bio-organic synthesis strategies for 12-OPDA and analogous substances have recently been established. The resulting availability of OPDA will aid the identification of additional effector proteins, help in elucidating the mechanisms of OPDA sensing and transmission, and will foster the analysis of the physiological responses to OPDA in plants. There is a need to determine the compartmentation and transport of 12-OPDA and its...Continue Reading

References

Sep 1, 1992·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Fukushima
May 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·A R BrashT M Harris
Oct 14, 1988·Biochemical and Biophysical Research Communications·M Hamberg
Apr 1, 1973·Journal of Pharmaceutical Sciences·D C MonkhouseA J Aguiar
Apr 1, 1966·Clinica Chimica Acta; International Journal of Clinical Chemistry·M Bygdeman, B Samuelsson
Sep 18, 1997·Proceedings of the National Academy of Sciences of the United States of America·H WeberE E Farmer
Oct 21, 1998·The Plant Journal : for Cell and Molecular Biology·D Laudert, E W Weiler
Jan 19, 1999·Annual Review of Cell and Developmental Biology·C A Ryan, G Pearce
Dec 2, 1999·Lipids·J ZieglerM Hamberg
Apr 12, 2000·Plant Physiology·S SivasankarS J Rothstein
Apr 13, 2001·Medicinal Research Reviews·D S Straus, C K Glass
May 15, 2001·Biochemical and Biophysical Research Communications·Y TsubouchiH Sano
Oct 11, 2001·Proceedings of the National Academy of Sciences of the United States of America·A StintziE E Farmer
Jun 13, 2002·The Plant Journal : for Cell and Molecular Biology·Inés Ponce De LeónCarmen Castresana
Nov 2, 2002·Angewandte Chemie·Martin Ernst, Günter Helmchen
Apr 26, 2003·The Plant Journal : for Cell and Molecular Biology·Ingeborg ThomaMartin J Mueller
Sep 27, 2003·The Journal of Organic Chemistry·Takayuki AinaiYuichi Kobayashi
Jul 3, 2004·Current Opinion in Plant Biology·Martin J Mueller
Dec 25, 2004·Plant Physiology·Christiane LoefflerMartin J Mueller
Jan 11, 2005·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Jose U Scher, Michael H Pillinger
Oct 21, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yoshiki KobayashiJunichi Chihara
Mar 3, 2006·The Journal of Clinical Investigation·Liliane Michalik, Walter Wahli
Dec 1, 1987·Plant Physiology·B A Vick, D C Zimmerman
Dec 30, 2006·Chembiochem : a European Journal of Chemical Biology·Birgit SchulzeWilhelm Boland
Jan 11, 2007·Journal of Experimental Botany·Theodora FarmakiJose J Sánchez-Serrano
Apr 5, 2007·Annals of the New York Academy of Sciences·Javier GayarreDolores Pérez-Sala
Jul 17, 2007·Toxicology and Applied Pharmacology·Hyun-Joung LimHyun-Young Park

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Citations

Sep 11, 2018·Plant, Cell & Environment·Vijay KumarKarl-Josef Dietz
Apr 27, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Natalia KłeczekAnna Stojakowska

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