The functional organization of the interictal spike complex in benign rolandic epilepsy

Epilepsia
C BaumgartnerA Lischka

Abstract

We studied the functional organization of the interictal epileptic spike complex in patients with benign rolandic epilepsy of childhood (BREC). We recorded interictal epileptiform spikes and somatosensory evoked potentials after median nerve stimulation, providing a biologic marker for the location of the central sulcus in 12 patients with BREC. We used multiple dipole modeling to assess the number, the three-dimensional intracerebral location, and the time activity of the underlying neuronal sources. Although the interictal spike complex could be modeled by a single tangential dipolar source in seven patients (group 1), in the remaining five patients, two sources-a radial and a tangential dipole-were necessary adequately to explain the interictal spikes (group 2). The tangential source was located deeper than the radial source and was characterized by a frontal positivity and a centroparietal negativity with a phase reversal across the central sulcus, suggesting that the interictal spikes originated in the anterior wall of the central sulcus. The radial source showed a single electronegativity over the ipsilateral central region, which would be compatible with involvement of the top of either the pre- or postcentral gyrus. Bot...Continue Reading

References

Sep 1, 1978·IEEE Transactions on Bio-medical Engineering·R N KavanaghD H Fender
Jan 1, 1992·Epilepsia·D L Gregory, P K Wong
Mar 1, 1992·Electroencephalography and Clinical Neurophysiology·C BaumgartnerW W Sutherling
Jan 1, 1991·Electroencephalography and Clinical Neurophysiology·C BaumgartnerW W Sutherling
Jul 1, 1991·Electroencephalography and Clinical Neurophysiology·C BaumgartnerD S Barth
Jan 1, 1991·Experimental Brain Research·C BaumgartnerW W Sutherling
Jan 1, 1991·Brain Topography·P K Wong
Apr 1, 1991·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
Jan 1, 1986·Electroencephalography and Clinical Neurophysiology·P L Nunez
Jan 1, 1987·Electroencephalography and Clinical Neurophysiology·F PerrinJ F Echallier
Jun 1, 1989·Electroencephalography and Clinical Neurophysiology·H SteinmetzB U Meyer
Nov 1, 1989·Journal of Neuroscience Methods·C BaumgartnerD S Barth
Jan 1, 1989·Brain Topography·P K Wong
Feb 1, 1989·IEEE Transactions on Bio-medical Engineering·M S Hämäläinen, J Sarvas
Mar 1, 1989·Acta paediatrica Scandinavica·S M Wolf, A Forsythe
Jan 1, 1988·Brain Topography·P K WongD Gregory
Jan 1, 1980·Progress in Brain Research·T M DarceyD H Fender
Jul 1, 1993·Electroencephalography and Clinical Neurophysiology·C BaumgartnerL Deecke
May 1, 1995·Electroencephalography and Clinical Neurophysiology·R G EmersonM Forgione
Jan 1, 1993·Brain Topography·H YoshinagaS Ohtahara
Jan 1, 1994·Acta Neurologica Scandinavica. Supplementum·J S Ebersole
Jan 1, 1993·Somatosensory & Motor Research·R Izraeli, L L Porter
Jan 1, 1993·Brain Topography·M Scherg, J S Ebersole
Jul 1, 1993·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·P K Wong
Jan 1, 1993·Epilepsia·G L Holmes

❮ Previous
Next ❯

Citations

Apr 7, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christoph Baumgartner
Sep 29, 1998·Electroencephalography and Clinical Neurophysiology·P ManganottiB Dalla Bernardina
Sep 12, 2003·Seizure : the Journal of the British Epilepsy Association·Yung-Yang LinRiitta Hari
Feb 27, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·I Merlet, J Gotman
Jul 31, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Geertjan HuiskampOnno van Nieuwenhuizen
Mar 7, 2014·Brain : a Journal of Neurology·Carolina CiumasPhilippe Ryvlin
Jan 22, 2003·Brain & Development·Shiro ChitokuO Carter Snead
Jan 1, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Ekaterina PataraiaChristoph Baumgartner
Sep 25, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C PlummerM J Cook
Feb 24, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R BoorP Stoeter
Sep 14, 2004·Mental Retardation and Developmental Disabilities Research Reviews·Kathryn A McVicar, Shlomo Shinnar
Jan 1, 2008·IEEE Reviews in Biomedical Engineering·Fernando H Lopes da Silva
Jun 27, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Kamran Ali SalayevKazuie Iinuma
Oct 5, 2002·Arquivos de neuro-psiquiatria·Nadia I O BragaJoão Antonio M Nobrega
Jul 26, 2003·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Gregory L Barkley, Christoph Baumgartner
Oct 3, 2003·Clinical EEG (electroencephalography)·Ki-Young JungDong Wook Kim
Feb 6, 2004·Arquivos de neuro-psiquiatria·Marcos H Coelho Duran, Lineu C Fonseca

❮ Previous
Next ❯

Related Concepts

Related Feeds

Benign Rolandic Epilepsy

Benign Rolandic epilepsy is a partial idiopathic epilepsy of childhood presenting with a nocturnal seizure and with a typical EEG showing centrotemporal spike and multifocal or generalized sharp slow waves. Here is the latest research.

Barrel cortex

Here is the latest research on barrel cortex, a region of somatosensory and motor corticies in the brain, which are used by animals that rely on whiskers for world exploration.