PMID: 9162109May 1, 1997Paper

The fungal mitochondrial genome project: evolution of fungal mitochondrial genomes and their gene expression

Current Genetics
B PaquinB F Lang

Abstract

The goal of the fungal mitochondrial genome project (FMGP) is to sequence complete mitochondrial genomes for a representative sample of the major fungal lineages; to analyze the genome structure, gene content, and conserved sequence elements of these sequences; and to study the evolution of gene expression in fungal mitochondria. By using our new sequence data for evolutionary studies, we were able to construct phylogenetic trees that provide further solid evidence that animals and fungi share a common ancestor to the exclusion of chlorophytes and protists. With a database comprising multiple mitochondrial gene sequences, the level of support for our mitochondrial phylogenies is unprecedented, in comparison to trees inferred with nuclear ribosomal RNA sequences. We also found several new molecular features in the mitochondrial genomes of lower fungi, including: (1) tRNA editing, which is the same type as that found in the mitochondria of the amoeboid protozoan Acanthamoeba castellanii; (2) two novel types of putative mobile DNA elements, one encoding a site-specific endonuclease that confers mobility on the element, and the other constituting a class of highly compact, structured elements; and (3) a large number of introns, whi...Continue Reading

Citations

Jul 17, 2008·Comparative and Functional Genomics·S KerscherU Brandt
Oct 31, 2007·Current Genetics·Willem A Man In 't VeldHarold J G Meijer
Aug 26, 1999·Trends in Genetics : TIG·S L Forsburg
Jan 23, 1999·Current Opinion in Genetics & Development·S E Douglas
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May 14, 1999·Trends in Plant Science·S KamounV G Vleeshouwers
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Mar 11, 2003·Nucleic Acids Research·C E BullerwellB F Lang
Nov 9, 2000·Molecular Biology and Evolution·B PaquinB F Lang
Aug 26, 1999·The Journal of Eukaryotic Microbiology·B F LangG Burger
Jun 26, 2007·Applied and Environmental Microbiology·Wei-Jen ChenMarie-France Corio-Costet
Feb 10, 2009·Applied and Environmental Microbiology·Anne BriolayVincent Bulone
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Apr 10, 2003·Eukaryotic Cell·Sophien Kamoun
Nov 10, 2001·Annual Review of Phytopathology·U Liane Rosewich, H Corby Kistler

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