The future of comparative effectiveness and relative efficacy of drugs: an international perspective

Journal of Comparative Effectiveness Research
Donna A MessnerMartina Garau

Abstract

Drug development takes place in a global marketplace, albeit with the USA and EU markets currently dominating. In the USA, demands for comparative effectiveness research have gained traction against a backdrop of health delivery reform, while European stakeholders deliberate the role of relative effectiveness in health technology assessment, trying to reduce the duplication of effort by regulators and health technology assessment bodies. In both arenas, drug-makers are faced with mounting drug development costs, and uncertainty over the types of evidence acceptable for a growing list of stakeholders. This article reports and compares future scenarios for evidence expectations for drugs for the USA and EU in 2020. The similarities, differences, and joint implications of the scenarios are considered to create an view of future evidence generation for drugs developed for these markets.

References

Apr 8, 2009·Journal of Clinical Epidemiology·Kevin E ThorpeKalipso Chalkidou
Jan 27, 2011·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Bengt Jönsson
Sep 3, 2013·The New England Journal of Medicine·Michael S Lauer, Ralph B D'Agostino
Mar 3, 2015·Journal of Comparative Effectiveness Research·Donna A MessnerAdrian Towse
Mar 6, 2015·Journal of Comparative Effectiveness Research·Adrian TowseDonna A Messner
May 29, 2015·The Onderstepoort Journal of Veterinary Research·Hezekiah K AdesokanRuth A Obaweda
Jun 18, 2015·Journal of Injury & Violence Research·Hosein KarimAlireza Ahmadi

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