The Future of Concurrent Automated Coronary Artery Calcium Scoring on Screening Low-Dose Computed Tomography

Curēus
Jeffrey WaltzJeremy R Burt

Abstract

Low-dose computed tomography (LDCT) has been extensively validated for lung cancer screening in selected patient populations. Additionally, the use of gated cardiac CT to assess coronary artery calcium (CAC) burden has been validated to determine a patient's risk for major cardiovascular adverse events. This is typically performed by calculating an Agatston score based on density and overall burden of calcified plaque within the coronary arteries. Patients that qualify for LDCT for lung cancer screening commonly share major risk factors for coronary artery disease and would frequently benefit from an additional gated cardiac CT for the assessment of CAC. Given the widespread use of LDCT for lung cancer screening, we evaluated current literature regarding the use of non-gated chest CT, specifically LDCT, for the detection and grading of coronary artery calcifications. Additionally, given the evolving and increasing use of artificial intelligence (AI) in the interpretation of radiologic studies, current literature for the use of AI in CAC assessment was reviewed.  We reviewed primary scientific literature dating up to April 2020 using Pubmed and Google Scholar, with the search terms low dose CT, lung cancer screening, coronary ar...Continue Reading

References

Mar 15, 1990·Journal of the American College of Cardiology·A S AgatstonR Detrano
Oct 25, 2002·American Journal of Epidemiology·Diane E BildRussell P Tracy
Aug 21, 2003·JAMA : the Journal of the American Medical Association·Philip GreenlandPeter W Wilson
Oct 27, 2006·The New England Journal of Medicine·UNKNOWN International Early Lung Cancer Action Program InvestigatorsOlli S Miettinen
Mar 22, 2008·AJR. American Journal of Roentgenology·Sung Mok KimBong-Keun Choe
Mar 28, 2008·The New England Journal of Medicine·Robert DetranoRichard A Kronmal
Nov 5, 2008·Medical Image Computing and Computer-assisted Intervention : MICCAI·Stefan C SaurPhilippe C Cattin
Jul 15, 2009·Archives of Internal Medicine·Kwang Pyo KimAmy Berrington de González
Jul 1, 2011·The New England Journal of Medicine·UNKNOWN National Lung Screening Trial Research TeamJoRean D Sicks
Sep 11, 2012·IEEE Transactions on Medical Imaging·Ivana IsgumBram van Ginneken
Sep 18, 2012·Academic Radiology·Rahil ShahzadWiro J Niessen
Jan 22, 2013·Journal of Cardiovascular Computed Tomography·Fabrice C DeprezEmmanuel Coche
May 24, 2013·The New England Journal of Medicine·Timothy R ChurchSarah Baum
Nov 14, 2013·Journal of the American Pharmacists Association : JAPhA
Jan 1, 2014·Annals of Internal Medicine·Virginia A Moyer, UNKNOWN U.S. Preventive Services Task Force
Nov 6, 2014·The New England Journal of Medicine·William C BlackUNKNOWN National Lung Screening Trial Research Team
Mar 21, 2015·IEEE Transactions on Medical Imaging·Jelmer M WolterinkIvana Isgum
Sep 21, 2015·European Journal of Epidemiology·Albert HofmanMeike W Vernooij
May 6, 2016·Medical Physics·Guanyu YangJean-Louis Coatrieux
Jul 22, 2018·Journal of the American College of Cardiology·Philip GreenlandKarol E Watson
Aug 21, 2018·Proceedings of SPIE·Carlos Cano-EspinosaRaúl San José Estépar
Nov 24, 2018·American Journal of Preventive Medicine·Thomas B RichardsMary C White
Nov 16, 2019·European Radiology·Mårten SandstedtAnders Persson
Jan 9, 2020·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal
Jan 18, 2020·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Pingkun YanMannudeep K Kalra

❮ Previous
Next ❯

Software Mentioned

AI

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.