The Future of Cryopreservation in Assisted Reproductive Technologies.

Frontiers in Endocrinology
Ernesto BoschPeter Humaidan

Abstract

Societal changes and the increasing desire and opportunity to preserve fertility have increased the demand for effective assisted reproductive technologies (ART) and have increased the range of scenarios in which ART is now used. In recent years, the "freeze-all" strategy of cryopreserving all oocytes or good quality embryos produced in an IVF cycle to transfer later-at a time that is more appropriate for reasons of medical need, efficacy, or desirability-has emerged as an accepted and valuable alternative to fresh embryo transfer. Indeed, improvements in cryopreservation techniques (vitrification) and the development of more efficient ovarian stimulation protocols have facilitated a dramatic increase in the practice of elective frozen embryo transfer (eFET). Alongside these advances, debate continues about whether eFET should be a standard treatment option available to the whole IVF population or if it is important to identify patient subgroups who are most likely to benefit from such an approach. Achieving successful outcomes in ART, whether by fresh or frozen embryo transfer, is influenced by a wide range of factors. As well as the efficiency of IVF and embryo transfer protocols and techniques, factors affecting implantation...Continue Reading

References

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Citations

Jun 20, 2020·Journal of Assisted Reproduction and Genetics·Jialyu HuangYanping Kuang
Aug 6, 2020·Genes·Martine De Rycke, Veerle Berckmoes
Jan 28, 2021·International Journal of Molecular Sciences·Irene PeinadoMaría José Gómez-Torres
Mar 17, 2021·Reproductive Biomedicine Online·Osamu IshiharaUNKNOWN Japanese Follitropin Delta Phase 3 Trial (STORK) Group
Apr 9, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Laurie HenryMichelle Nisolle
May 26, 2021·Reproductive Sciences·Michail KalinderisRoy Homburg

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