Oct 2, 2019

The future of cystic fibrosis care: a global perspective

The Lancet. Respiratory Medicine
Scott C BellFelix Ratjen

Abstract

The past six decades have seen remarkable improvements in health outcomes for people with cystic fibrosis, which was once a fatal disease of infants and young children. However, although life expectancy for people with cystic fibrosis has increased substantially, the disease continues to limit survival and quality of life, and results in a large burden of care for people with cystic fibrosis and their families. Furthermore, epidemiological studies in the past two decades have shown that cystic fibrosis occurs and is more frequent than was previously thought in populations of non-European descent, and the disease is now recognised in many regions of the world. The Lancet Respiratory Medicine Commission on the future of cystic fibrosis care was established at a time of great change in the clinical care of people with the disease, with a growing population of adult patients, widespread genetic testing supporting the diagnosis of cystic fibrosis, and the development of therapies targeting defects in the cystic fibrosis transmembrane conductance regulator (CFTR), which are likely to affect the natural trajectory of the disease. The aim of the Commission was to bring to the attention of patients, health-care professionals, researcher...Continue Reading

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Mentioned in this Paper

Enzyme Replacement Therapy
Cystic-fibrosis Membrane-conductance-regulating Protein Activity
Research
Diet
Genetic Screening Method
Multidisciplinary Care Plan
Research Personnel
Disease Eradication
Cystic Fibrosis
Persons

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