The future of hybrid imaging-part 3: PET/MR, small-animal imaging and beyond.

Insights Into Imaging
Thomas BeyerDavid W Townsend

Abstract

Since the 1990s, hybrid imaging by means of software and hardware image fusion alike allows the intrinsic combination of functional and anatomical image information. This review summarises in three parts the state of the art of dual-technique imaging with a focus on clinical applications. We will attempt to highlight selected areas of potential improvement of combined imaging technologies and new applications. In this third part, we discuss briefly the origins of combined positron emission tomography (PET)/magnetic resonance imaging (MRI). Unlike PET/computed tomography (CT), PET/MRI started out from developments in small-animal imaging technology, and, therefore, we add a section on advances in dual- and multi-modality imaging technology for small animals. Finally, we highlight a number of important aspects beyond technology that should be addressed for a sustained future of hybrid imaging. In short, we predict that, within 10 years, we may see all existing multi-modality imaging systems in clinical routine, including PET/MRI. Despite the current lack of clinical evidence, integrated PET/MRI may become particularly important and clinically useful in improved therapy planning for neurodegenerative diseases and subsequent respon...Continue Reading

References

Apr 1, 1995·Physics in Medicine and Biology·N L ChristensenK Fetterly
Nov 26, 1999·JAMA : the Journal of the American Medical Association·J M Eisenberg
Jul 21, 2000·Medical Physics·M M GoodsittL Hadjiiski
Aug 10, 2000·Neoplasia : an International Journal for Oncology Research·S S GambhirR Blasberg
Mar 5, 2003·Technology in Cancer Research & Treatment·Mark B WilliamsAlex Stewart
Dec 25, 2003·JAMA : the Journal of the American Medical Association·Gerald AntochStefan G Ruehm
Nov 3, 2005·Physics in Medicine and Biology·Steven R MeikleRichard B Banati
Jul 27, 2006·Technology in Cancer Research & Treatment·Douglas J WagenaarBradley E Patt
Jul 4, 2007·European Journal of Nuclear Medicine and Molecular Imaging·Angelika Bischof DelaloyeBruno Silberman
Aug 22, 2007·Radiology·Martin S JudenhoferBernd J Pichler
Dec 18, 2007·Nuklearmedizin. Nuclear Medicine·B J KrauseN Willich
Feb 12, 2008·Physics in Medicine and Biology·D W Townsend
Feb 20, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Thomas BeyerAndreas Bockisch
Apr 1, 2008·Nature Medicine·Martin S JudenhoferBernd J Pichler
Apr 9, 2008·Seminars in Nuclear Medicine·Bernd J PichlerMartin S Judenhofer
Aug 20, 2008·Radiology·Heinz-Peter W SchlemmerClaus D Claussen
Aug 20, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·John V Frangioni
Oct 18, 2008·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Matthias HofmannBernd J Pichler
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Stephan G NekollaAntti Saraste
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Mathias Goyen, Jörg F Debatin
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Wolf-Dieter Heiss
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Gerald Antoch, Andreas Bockisch
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Gunnar BrixJürgen Griebel
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Thomas Beyer, Bernd Pichler
Dec 24, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Matthias HofmannThomas Beyer
Dec 25, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Roger Lecomte
Feb 6, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Hans F WehrlBernd J Pichler
Mar 3, 2009·Radiology·Bingsheng HuangPek-Lan Khong
May 30, 2009·Physics in Medicine and Biology·P MadhavM P Tornai
Aug 4, 2009·Seminars in Nuclear Medicine·Simon R Cherry
Oct 28, 2009·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·S HahnG Antoch
Nov 17, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Ronald BoellaardBernd J Krause
Jan 21, 2010·Nuklearmedizin. Nuclear Medicine·J KotzerkeA Bockisch
Feb 9, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Gustav K von Schulthess, Cyrill Burger
Feb 13, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Bernd J PichlerHeinz-Peter Schlemmer
Feb 19, 2010·Physics in Medicine and Biology·Mark J HamamuraOrhan Nalcioglu
Mar 4, 2010·Journal of Nuclear Medicine Technology·Andreas K BuckJonas Schreyögg
Mar 9, 2010·Physics in Medicine and Biology·Armin KolbBernd J Pichler
Mar 20, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Marion de Jong, Theodosia Maina
May 5, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Vincent KeeremanStefaan Vandenberghe
Jul 27, 2010·Radiology·Anwar R Padhani, Kenneth A Miles
Jul 28, 2010·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Andreas BossLars Stegger
Jan 15, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Thomas BeyerLutz S Freudenberg
Feb 11, 2011·European Journal of Nuclear Medicine and Molecular Imaging·Frederic MantlikThomas Beyer

❮ Previous
Next ❯

Citations

Jan 9, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Claes Nøhr LadefogedThomas Beyer
Feb 7, 2013·Magma·Thomas Beyer, Ewald Moser
Mar 22, 2013·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Dale L BaileyHans F Wehrl
May 2, 2013·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Sharif KershahPeter Faulhaber
Oct 23, 2013·Molecular Diagnosis & Therapy·Lídia CunhaLuís F Metello
Dec 3, 2013·European Journal of Nuclear Medicine and Molecular Imaging·K KubiessaP Stumpp
Nov 29, 2013·Journal of Labelled Compounds & Radiopharmaceuticals·Hancheng Cai, Peter S Conti
Aug 21, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Fatih GokselIrfan Sencan
Sep 2, 2014·BioMed Research International·Victoria SherwoodGail R ter Haar
Aug 12, 2016·Clinical and Translational Imaging : Reviews in Nuclear Medicine and Molecular Imaging·Marjolein HeukerMarleen van Oosten
Jan 19, 2013·Molecular Pharmaceutics·Katie L CiesienskiPeter Caravan
Jun 16, 2012·Journal of the American Chemical Society·Ritika UppalPeter Caravan
Feb 10, 2018·European Journal of Nuclear Medicine and Molecular Imaging·T BeyerL S Freudenberg
Jul 30, 2020·Advanced Drug Delivery Reviews·Carlos Pérez-MedinaRoy van der Meel

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging technique
surgical resection
X-ray
imaging techniques
ESR
imaging technology

Software Mentioned

EANM
BrainPET
ALARA
ESR

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Ciprian CatanaBruce Rosen
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Andreas BossLars Stegger
© 2022 Meta ULC. All rights reserved