The G protein alpha subunit (GP alpha1) is associated with the ER and the plasma membrane in meristematic cells of Arabidopsis and cauliflower

FEBS Letters
C A WeissH Ma

Abstract

Towards the elucidation of the cellular function(s) of GP alpha1, we have characterized its subcellular localization using immunofluorescence and cell fractionation. GP alpha1 is not present in nuclei or chloroplasts. It is a membrane-bound protein, and analysis of isolated endoplasmic and plasma membranes indicates a good correlation between GP alpha1 in both the plasma membrane and the ER compartment. Interestingly, these results may suggest more different functions for GP alpha1: it might be involved in transmission of extracellular signals across the plasma membrane and in the cytoplasm, and/or it may also be involved in regulating some aspects of the ER functions or membrane trafficking between both membranes.

References

Apr 1, 1978·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·P LaurilaS Stenman
Jan 1, 1991·Annual Review of Biochemistry·H G DohlmanR J Lefkowitz
Jun 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·L ErcolaniD A Ausiello
May 10, 1991·Science·M I SimonN Gautam
May 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·H MaE M Meyerowitz
Dec 1, 1994·Plant Molecular Biology·H Ma
Sep 27, 1994·Proceedings of the National Academy of Sciences of the United States of America·C A WeissH Ma
Jan 1, 1994·Annual Review of Biochemistry·C Nuoffer, W E Balch
Jun 24, 1996·FEBS Letters·B Nürnberg, G Ahnert-Hilger
Apr 1, 1992·Trends in Cell Biology·F A BarrW B Huttner
Mar 1, 1992·Current Biology : CB·W E Balch
Jan 14, 1994·Science·A M Jones

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Citations

Nov 4, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R Hooley
Jun 18, 2002·Plant Physiology·Hemayet UllahAlan M Jones
Sep 13, 2011·Cellular Signalling·Thamara Hewavitharana, Philip B Wedegaertner
Aug 28, 2001·Plant & Cell Physiology·Y FujisawaY Iwasaki
Feb 15, 2013·Pharmacological Reviews·Shahriar M KhanTerence E Hébert
Mar 11, 2008·The Journal of Biological Chemistry·Shiyu WangNina V Fedoroff
Dec 13, 2006·Journal of Cell Science·Merel J W Adjobo-HermansTheodorus W J Gadella
Jul 1, 2001·The New Phytologist·P A Millner

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