The Gastric Microbiome and Its Influence on Gastric Carcinogenesis: Current Knowledge and Ongoing Research

Hematology/oncology Clinics of North America
Chao ZhangManish A Shah

Abstract

Gastric malignancies are a leading cause of cancer-related death worldwide. At least 2 microbial species are currently linked to carcinogenesis and the development of cancer within the human stomach. These include the bacterium Helicobacter pylori and the Epstein-Barr virus. In recent years, there has been increasing evidence that within the human gastrointestinal tract it is not only pathogenic microbes that impact human health but also the corresponding autochthonous microbial communities. This article reviews the gastrointestinal microbiome as it relates primarily to mechanisms of disease and carcinogenesis within the upper gastrointestinal tract.

Citations

Apr 13, 2018·American Journal of Clinical Pathology·Mark A BenedictDhanpat Jain
Oct 19, 2017·Nature Reviews. Gastroenterology & Hepatology·Manish A Shah
Apr 4, 2018·Journal of Clinical Biochemistry and Nutrition·Toshio Kobayashi, Akira Andoh
Jun 20, 2020·World Journal of Gastroenterology : WJG·Preeti SharmaShanmugarajah Rajendra
May 2, 2020·International Journal of Molecular Sciences·Maria Manuel AzevedoFátima Baltazar
Nov 30, 2018·World Journal of Gastroenterology : WJG·Carolina Rosal Teixeira de SouzaRommel Mario Rodríguez Burbano
Mar 7, 2020·Alimentary Pharmacology & Therapeutics·Boldbaatar GantuyaYoshio Yamaoka
May 13, 2018·International Journal of Molecular Sciences·Jackie Li, Guillermo I Perez Perez
Sep 15, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·An-Qi LiuWen Chen
Jul 10, 2020·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Manish A ShahHeinz-Josef Lenz
Sep 10, 2021·Revista Española De Enfermedades Digestivas : Organo Oficial De La Sociedad Española De Patología Digestiva·Lisset Barroso MárquezHarlim Rodríguez Rodríguez

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