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The gastrointestinal absorption of methadone in the rat

Drug Metabolism and Disposition : the Biological Fate of Chemicals

Jan 1, 1975

C T WalshC Squires

PMID: 1229

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Abstract

The absorption of dl-methadone from the gastrointestinal tract of the Sprague-Dawley rat was examined by the in vivo segment technique. Duodenal absorption, measured as a function of time and dose, followed first-order kinetics with a half-life of 15.6 min. Absorption was not influenced...read more

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Jejunum
Stomach
Duodenum
Symoron
Cecum
Intestinal Absorption
Ileum
Pharmaceutical Vehicles
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  • The gastrointestinal absorption of methadone in the rat

    Drug Metabolism and Disposition : the Biological Fate of Chemicals

    Jan 1, 1975

    C T WalshC Squires

    PMID: 1229

    DOI:

    Abstract

    The absorption of dl-methadone from the gastrointestinal tract of the Sprague-Dawley rat was examined by the in vivo segment technique. Duodenal absorption, measured as a function of time and dose, followed first-order kinetics with a half-life of 15.6 min. Absorption was not influenced...read more

    Mentioned in this Paper

    Jejunum
    Stomach
    Duodenum
    Symoron
    Cecum

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